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Current Drug Therapy

New therapies for type 2 diabetes based on glucagon-like peptide 1

Marzieh Salehi, MD and David A. D’alessio, MD
Cleveland Clinic Journal of Medicine April 2006, 73 (4) 382-389;
Marzieh Salehi
Division of Endocrinology and Metabolism, University of Cincinnati Medical Center, Cincinnati, OH
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David A. D’alessio
Division of Endocrinology and Metabolism, University of Cincinnati Medical Center, Cincinnati, OH
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ABSTRACT

Cells in the gastrointestinal tract secrete several hormones that stimulate insulin secretion, one of which is glucagon-like peptide (GLP-1). Several new drugs act through the GLP-1 signaling system to stimulate insulin release and regulate blood glucose levels in patients with diabetes. One such compound, exenatide (Byetta), has recently become available, and others are in clinical development.

  • © 2006 The Cleveland Clinic Foundation. All Rights Reserved.
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Cleveland Clinic Journal of Medicine: 73 (4)
Cleveland Clinic Journal of Medicine
Vol. 73, Issue 4
1 Apr 2006
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New therapies for type 2 diabetes based on glucagon-like peptide 1
Marzieh Salehi, David A. D’alessio
Cleveland Clinic Journal of Medicine Apr 2006, 73 (4) 382-389;

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New therapies for type 2 diabetes based on glucagon-like peptide 1
Marzieh Salehi, David A. D’alessio
Cleveland Clinic Journal of Medicine Apr 2006, 73 (4) 382-389;
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