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Review

Congenital long QT syndrome: Considerations for primary care physicians

Ethan Levine, DO, Spencer Z. Rosero, MD, Adam S. Budzikowski, MD, PhD, Arthur J. Moss, MD, Wojciech Zareba, MD, PhD and James P. Daubert, MD
Cleveland Clinic Journal of Medicine August 2008, 75 (8) 591-600;
Ethan Levine
Cardiology Division, Department of Medicine, University of Rochester Medical Center, Rochester, NY
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Spencer Z. Rosero
Cardiology Division, Department of Medicine, University of Rochester Medical Center, Rochester, NY
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Adam S. Budzikowski
Cardiology Division, Department of Medicine, University of Rochester Medical Center, Rochester, NY
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Arthur J. Moss
Cardiology Division, Department of Medicine, University of Rochester Medical Center, Rochester, NY
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Wojciech Zareba
Cardiology Division, Department of Medicine, University of Rochester Medical Center, Rochester, NY
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James P. Daubert
Associate Professor of Medicine, and Cardiology Division, Department of Medicine, University of Rochester Medical Center, Rochester, NY
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ABSTRACT

Congenital long QT syndrome is an inherited disorder of cardiac repolarization that predisposes to syncope and to sudden death from polymorphic ventricular tachycardia. The disorder should be suspected when the electrocardiogram shows characteristic QT abnormalities, or when there is a family history of long QT syndrome or of an event that raises suspicion of long QT syndrome, such as sudden death, syncope, or ill-defined “seizure” disorder. We can now classify some types of congenital long QT syndrome according to their genetic mutations and their triggers, such as exercise, rest, or startle.

Footnotes

  • ↵* Dr. Daubert has disclosed that he has received consulting fees from Medtronic and CryoCor corporations and has ownership interest in Boston Scientific.

  • Copyright © 2008 The Cleveland Clinic Foundation. All Rights Reserved.
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Cleveland Clinic Journal of Medicine: 75 (8)
Cleveland Clinic Journal of Medicine
Vol. 75, Issue 8
1 Aug 2008
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Congenital long QT syndrome: Considerations for primary care physicians
Ethan Levine, Spencer Z. Rosero, Adam S. Budzikowski, Arthur J. Moss, Wojciech Zareba, James P. Daubert
Cleveland Clinic Journal of Medicine Aug 2008, 75 (8) 591-600;

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Congenital long QT syndrome: Considerations for primary care physicians
Ethan Levine, Spencer Z. Rosero, Adam S. Budzikowski, Arthur J. Moss, Wojciech Zareba, James P. Daubert
Cleveland Clinic Journal of Medicine Aug 2008, 75 (8) 591-600;
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