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Review

Statin myopathy: A common dilemma not reflected in clinical trials

Genaro Fernandez, MD, Erica S. Spatz, MD, Charles Jablecki, MD and Paul S. Phillips, MD
Cleveland Clinic Journal of Medicine June 2011, 78 (6) 393-403; DOI: https://doi.org/10.3949/ccjm.78a.10073
Genaro Fernandez
Internal Medicine Residency Program, The University of Utah, Salt Lake City
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Erica S. Spatz
Robert Wood Johnson Clinical Scholars Program, Cardiovascular Disease Fellow, Yale University School of Medicine, New Haven, CT
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Charles Jablecki
Department of Neurosciences, University of California San Diego, La Jolla
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Paul S. Phillips
Director, Interventional Cardiology, Department of Cardiology, Scripps Mercy Hospital, San Diego, CA
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ABSTRACT

Although statins are remarkably effective, they are still underprescribed because of concerns about muscle toxicity. We review the aspects of statin myopathy that are important to the primary care physician and provide a guide for evaluating patients on statins who present with muscle complaints. We outline the differential diagnosis, the risks and benefits of statin therapy in patients with possible toxicity, and the subsequent treatment options.

  • Copyright © 2011 The Cleveland Clinic Foundation. All Rights Reserved.
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Cleveland Clinic Journal of Medicine: 78 (6)
Cleveland Clinic Journal of Medicine
Vol. 78, Issue 6
1 Jun 2011
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Statin myopathy: A common dilemma not reflected in clinical trials
Genaro Fernandez, Erica S. Spatz, Charles Jablecki, Paul S. Phillips
Cleveland Clinic Journal of Medicine Jun 2011, 78 (6) 393-403; DOI: 10.3949/ccjm.78a.10073

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Statin myopathy: A common dilemma not reflected in clinical trials
Genaro Fernandez, Erica S. Spatz, Charles Jablecki, Paul S. Phillips
Cleveland Clinic Journal of Medicine Jun 2011, 78 (6) 393-403; DOI: 10.3949/ccjm.78a.10073
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