Genetics and hepatitis C: It’s good to be ‘CC’

Jose Mari Parungao; Ibrahim A. Hanouneh; Binu John; Naim Alkhouri; Nizar N. Zein

doi:10.3949/ccjm.82a.14004

Genetics and hepatitis C: It’s good to be ‘CC’

Jose Mari Parungao, MD
Jose Mari Parungao
Department of Gastroenterology, Providence Hospital and Medical Centers, Southfield, MI
MD
Ibrahim A. Hanouneh, MD
Ibrahim A. Hanouneh
Department of Gastroenterology and Hepatology, Digestive Disease Institute, Cleveland Clinic; Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
MD
Binu John, MD
Binu John
Department of Gastroenterol-ogy and Hepatology, Digestive Disease Institute, Cleveland Clinic; Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
MD
Naim Alkhouri, MD
Naim Alkhouri
Department of Gastroenterology and Hepatology, Digestive Disease Institute, Cleveland Clinic
MD
and Nizar N. Zein, MD
Nizar N. Zein
Department of Gastroenterol-ogy and Hepatology, Digestive Disease Institute, Cleveland Clinic; Associate Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
MD
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- For correspondence: [email protected]

Cleveland Clinic Journal of Medicine
February 2015,
82
(2)
97-104;
DOI: https://doi.org/10.3949/ccjm.82a.14004

ABSTRACT

The interleukin-28B (IL28B) gene contains a single-nucleotide polymorphism at location rs12979860 that affects both the natural history of hepatitis C virus infection and the patient’s response to treatment, particularly interferon-based regimens with or without protease inhibitors.

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Genetics and hepatitis C: It’s good to be ‘CC’

Jose Mari Parungao

Jose Mari Parungao

Ibrahim A. Hanouneh

Ibrahim A. Hanouneh

Binu John

Binu John

Naim Alkhouri

Naim Alkhouri

and Nizar N. Zein

Nizar N. Zein

Cleveland Clinic Journal of Medicine

February 2015,

82

(2)

97-104;

DOI: 10.3949/ccjm.82a.14004

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Genetics and hepatitis C: It’s good to be ‘CC’

Jose Mari Parungao

Jose Mari Parungao

Ibrahim A. Hanouneh

Ibrahim A. Hanouneh

Binu John

Binu John

Naim Alkhouri

Naim Alkhouri

and Nizar N. Zein

Nizar N. Zein

Cleveland Clinic Journal of Medicine

February 2015,

82

(2)

97-104;

DOI: 10.3949/ccjm.82a.14004

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