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Review

Resuming anticoagulation after hemorrhage: A practical approach

Alison Colantino, MD, Amir K. Jaffer, MD, MBA and Daniel J. Brotman, MD
Cleveland Clinic Journal of Medicine April 2015, 82 (4) 245-256; DOI: https://doi.org/10.3949/ccjm.82a.14047
Alison Colantino
Department of Medicine, Johns Hopkins University, Baltimore, MD
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Amir K. Jaffer
Department of Internal Medicine, Rush Medical College, Chicago, IL
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Daniel J. Brotman
Department of Medicine, Johns Hopkins University, Baltimore, MD
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ABSTRACT

Most patients who suffer a hemorrhage while on long-term anticoagulant therapy continue to be at risk of thrombosis. Physicians often need to reconsider the need for anticoagulation in view of the risk of recurrent bleeding, and when anticoagulation needs to be resumed, they must also consider the timing and strategy. Since there are no evidence-based guidelines for these situations, the authors of this paper offer a practical framework for individualizing the resumption of anticoagulation after hemorrhage.

Footnotes

  • ↵* Dr. Jaffer has disclosed consulting for AstraZeneca, Boehringer-Ingelheim, Janssen Pharmaceuticals, Marathon, and Pfizer; receiving grant and research support from AstraZeneca and the National Heart, Lung, and Blood Institute; and board membership in the Society of Perioperative Assessment and Quality Improvement.

  • Dr. Brotman has disclosed consulting for the Maven Corporation.

  • Copyright © 2015 The Cleveland Clinic Foundation. All Rights Reserved.
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Cleveland Clinic Journal of Medicine: 82 (4)
Cleveland Clinic Journal of Medicine
Vol. 82, Issue 4
1 Apr 2015
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Resuming anticoagulation after hemorrhage: A practical approach
Alison Colantino, Amir K. Jaffer, Daniel J. Brotman
Cleveland Clinic Journal of Medicine Apr 2015, 82 (4) 245-256; DOI: 10.3949/ccjm.82a.14047

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Resuming anticoagulation after hemorrhage: A practical approach
Alison Colantino, Amir K. Jaffer, Daniel J. Brotman
Cleveland Clinic Journal of Medicine Apr 2015, 82 (4) 245-256; DOI: 10.3949/ccjm.82a.14047
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