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1-Minute Consult

Should I refer my patient for a parathyroidectomy?

Gustavo Romero-Velez, MD, Leila Zeinab Khan, MD and Judy Jin, MD
Cleveland Clinic Journal of Medicine May 2024, 91 (5) 279-280; DOI: https://doi.org/10.3949/ccjm.91a.23076
Gustavo Romero-Velez
Department of Endocrine Surgery, Cleveland Clinic, Cleveland, OH; Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
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Leila Zeinab Khan
Department of Endocrinology, Diabetes, and Metabolism, Cleveland Clinic, Cleveland, OH; Medical Director of the Calcium Center, Cleveland Clinic, Cleveland, OH; Clinical Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
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Judy Jin
Department of Endocrine Surgery, Cleveland Clinic, Cleveland, OH; Surgical Director of the Calcium Center, Cleveland Clinic, Cleveland, OH; Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
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    TABLE 1

    International criteria for parathyroid surgery in patients with primary hyperparathyroidism

    Surgery is recommended in all patients with at least 1 of the following:
    • Serum calcium > 1.0 mg/dL (0.25 mmol/L) above the upper limit of normal

    • Bone mineral density by dual-energy x-ray absorptiometry: T-score ≤ −2.5 at lumbar spine, total hip, femoral neck, or distal one-third radius

    • Vertebral fracture by radiography, computed tomography, or magnetic resonance imaging

    • Estimated glomerular filtration rate or creatinine clearance < 60 mL/minute

    • 24-hour urine calcium level > 250 mg in women and > 300 mg in men

    • Presence of nephrolithiasis or nephrocalcinosis by radiography, ultrasonography, or computed tomography

    • Age < 50

    • Based on information in reference 2.

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Cleveland Clinic Journal of Medicine: 91 (5)
Cleveland Clinic Journal of Medicine
Vol. 91, Issue 5
1 May 2024
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Should I refer my patient for a parathyroidectomy?
Gustavo Romero-Velez, Leila Zeinab Khan, Judy Jin
Cleveland Clinic Journal of Medicine May 2024, 91 (5) 279-280; DOI: 10.3949/ccjm.91a.23076

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Should I refer my patient for a parathyroidectomy?
Gustavo Romero-Velez, Leila Zeinab Khan, Judy Jin
Cleveland Clinic Journal of Medicine May 2024, 91 (5) 279-280; DOI: 10.3949/ccjm.91a.23076
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