More articles from Editorial
- Surgical de-escalation: Are we ready for ‘observation’ of benign high-risk breast lesions found on core needle biopsy?
Surgical de-escalation is part of a larger movement of de-escalation of multidisciplinary breast cancer treatment. The challenge is to balance oncologic outcomes with surgical morbidity and quality of life.
- Reincarnating autoimmunity: Immune-related adverse events as new diseases
The range of adverse events is broad. Any organ can be affected, and any naturally occurring autoimmune process can be mimicked by the massive inflammation generated by checkpoint inhibition.
- Vitamin D: A metabolic bone disease perspective
When checking levels, clinicians should keep in mind that vitamin D levels fluctuate by season and time of day, and that different laboratories may use different assays that yield different results.
- Making best use of bone turnover markers to monitor oral bisphosphonate therapy
Clinical applications of bone turnover markers can include determining when to start or end a bisphosphonate “holiday” and measuring treatment response.
- Laboratory stewardship should be a priority in every hospital
Considerations include indirect costs, downstream testing or other workup based on minor abnormalities uncovered during daily testing, and shortages in staff and supplies.
- Psychogenic nonepileptic seizure: A neurologist’s perspective
Confirming the diagnosis is only the start of the journey. The greater challenge and opportunity lie in how physicians present the diagnosis to the patient and family.
- Glycemic targets in the ICU: A look back, and ahead
Much work is still needed to understand the nuances of glycemic targets in critically ill patients, and to learn how to take advantage of evolving technology to improve glycemic control.
- Fungus among us: A poster child for diagnostic stewardship
When interpreting the significance of Aspergillus species in respiratory culture, first ask if the culture was clinically indicated, or if this was an incidental finding.
- Famous and not-so-famous physical findings in infectious endocarditis: A look back
It is difficult to find a disease more emblematic of the practice of internal medicine.
- Calcium pyrophosphate deposition and crowned dens syndrome
Patients are typically over age 65, often with significant leukocytosis and dramatically elevated inflammatory markers.