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COVID-19 Curbside Consults

Update to post-acute sequelae of SARS-CoV-2 infection: Caring for the 'long-haulers'

Susan Vehar, MD, Marina Boushra, MD, Prince Ntiamoah, MD and Michelle Biehl, MD, MS
Cleveland Clinic Journal of Medicine October 2021, DOI: https://doi.org/10.3949/ccjm.88a.21010-up
Susan Vehar
Department of Critical Care Medicine; Department of Pulmonary Medicine; Cleveland Clinic, Cleveland, OH
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  • For correspondence: [email protected]
Marina Boushra
Department of Critical Care Medicine, Cleveland Clinic, Cleveland, OH
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Prince Ntiamoah
Department of Critical Care Medicine; Department of Pulmonary Medicine; Cleveland Clinic, Cleveland, OH
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Michelle Biehl
Department of Critical Care Medicine; Department of Pulmonary Medicine; Cleveland Clinic, Cleveland, OH
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    Figure 1

    Care pathway for patients with the post-acute sequelae of SARS-CoV-2 infection.

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    TABLE 1

    Prevalence of COVID-19 symptoms in a series of 143 cases

    Symptom% of patients
    At onsetAt 60 days
    Fatigue7956
    Dyspnea6742
    Joint pain5626
    Chest pain4022
    Cough7018
    Anosmia4317
    Sicca symptoms2216
    Rhinitis3212
    Red eyes2710
    Dysgeusia5010
    Headache508
    Sputum production187
    Lack of appetite567
    Sore throat306
    Vertigo185
    Myalgia565
    Diarrhea302
    • Data from Carfi et al, reference 7.

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Cleveland Clinic Journal of Medicine: 92 (5)
Cleveland Clinic Journal of Medicine
Vol. 92, Issue 5
1 May 2025
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Update to post-acute sequelae of SARS-CoV-2 infection: Caring for the 'long-haulers'
Susan Vehar, Marina Boushra, Prince Ntiamoah, Michelle Biehl
Cleveland Clinic Journal of Medicine Oct 2021, DOI: 10.3949/ccjm.88a.21010-up

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Update to post-acute sequelae of SARS-CoV-2 infection: Caring for the 'long-haulers'
Susan Vehar, Marina Boushra, Prince Ntiamoah, Michelle Biehl
Cleveland Clinic Journal of Medicine Oct 2021, DOI: 10.3949/ccjm.88a.21010-up
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  • Article
    • ABSTRACT
    • INTRODUCTION
    • TRUE NUMBERS ARE HARD TO ASSESS
    • MECHANISMS PROPOSED, BUT PATHOPHYSIOLOGY UNKNOWN
    • A RANGE OF SYMPTOMS
    • EVALUATION OF LONG-HAULERS
    • SPECIFIC TREATMENT FOR SYMPTOMS AND COMORBID CONDITIONS
    • VACCINATION
    • LIMITATIONS OF CURRENT DATA, AND LESSONS LEARNED
    • FUTURE DIRECTIONS
    • DISCLOSURES
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