Latest Articles

  • A perspective on discussing COVID-19 vaccines: Efficacy and adverse effects
    Brian F. Mandell, MD
    Cleveland Clinic Journal of Medicine December 2021, 88 (12) 644-645; DOI: https://doi.org/10.3949/ccjm.88b.12021

    Physicians should be vigilant and open-minded regarding possible adverse reactions to the vaccines, and should take time to discuss the demonstrated efficacy of vaccines with patients.

  • In Reply: Physician resistance to obesity pharmacotherapy
    Yael Mauer, MD, MPH, Marcie Parker, PharmD, BCACP and Sangeeta Kashyap, MD
    Cleveland Clinic Journal of Medicine December 2021, 88 (12) 658-659; DOI: https://doi.org/10.3949/ccjm.88c.12004
  • Should my older adult patients take aspirin for primary prevention of cardiovascular disease?
    Robert M. Zimbroff, MD, Gina Ayers, PharmD, BCPS, BCGP and Kenneth Koncilja, MD
    Cleveland Clinic Journal of Medicine November 2021, 88 (11) 632-634; DOI: https://doi.org/10.3949/ccjm.88a.21024

    For patients age 70 and older, recent evidence shows that the harms outweigh the benefits.

  • Another influenza season in the shadow of the COVID-19 pandemic
    Another influenza season in the shadow of the COVID-19 pandemic
    Sherif Beniameen Mossad, MD, FACP, FIDSA, FAST
    Cleveland Clinic Journal of Medicine November 2021, 88 (11) 594-597; DOI: https://doi.org/10.3949/ccjm.88a.21095

    Flu season is upon us at the ominous milestone of more than 722,000 US deaths from COVID-19.

  • Options for preserving fertility in women undergoing gonadotoxic treatment
    Laura Detti, MD
    Cleveland Clinic Journal of Medicine November 2021, 88 (11) 607-612; DOI: https://doi.org/10.3949/ccjm.88gr.21001

    For females undergoing cancer therapy, proactive treatments can help preserve the possibility of having children.

  • SGLT-2 inhibitors are potential game-changers (for more than diabetes)
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine November 2021, 88 (11) 588-589; DOI: https://doi.org/10.3949/ccjm.88b.11021

    Data from large clinical trials and improved understanding of the biologic effects of these drugs are changing expectations for the clinical course in patients with diabetes, as well as chronic kidney disease and heart failure.

  • Elevated hCG can be a benign finding in perimenopausal and postmenopausal women
    Lea El Hage, MD and Betul Hatipoglu, MD
    Cleveland Clinic Journal of Medicine November 2021, 88 (11) 635-639; DOI: https://doi.org/10.3949/ccjm.88a.18069

    A search for the source of the elevation in perimenopausal and postmenopausal women who are not pregnant and have no disease or tumor may delay patient care.

  • DXA and clinical challenges of fracture risk assessment in primary care
    Susan Williams, MS, RD, MD, CCD, FACP, FACE, Leila Khan, MD and Angelo A. Licata, MD, PhD, FACP, FACE
    Cleveland Clinic Journal of Medicine November 2021, 88 (11) 615-622; DOI: https://doi.org/10.3949/ccjm.88a.20199

    Overdependence on dual-energy x-ray absorptiometry, especially for patient populations the test was not designed for, may lead to poor clinical decisions.

  • SGLT-2 inhibitors in heart failure: Time for broader eligibility and earlier initiation
    Enrico G. Ferro, MD, Bertram Pitt, MD and Deepak L. Bhatt, MD, MPH
    Cleveland Clinic Journal of Medicine November 2021, 88 (11) 601-606; DOI: https://doi.org/10.3949/ccjm.88a.21045

    SGLT-2 inhibitors remain vastly underused in clinical practice despite their broad cardiorenal benefits.

  • Gastrointestinal varicella-zoster virus infection
    Nobukazu Agatsuma, MD, Kaoru Tsujioka, MD, Yoshitaka Nishikawa, MD, PhD, Yasuki Nakatani, MD and Yukitaka Yamashita, MD, PhD
    Cleveland Clinic Journal of Medicine November 2021, 88 (11) 592-593; DOI: https://doi.org/10.3949/ccjm.88a.20151

    Esophagogastroduodenoscopy showed small, shallow ulcers and erosions surrounded by red haloes, spread diffusely throughout the stomach and duodenum.

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