Latest Articles

  • The cost of ‘free’: Advising patients about sponsored genetic testing
    Stephanie Allison Larson, PhD, HEC-C, Joseph Liu, MS, David Flannery, MD, Marsha Michie, PhD and Paul J. Ford, PhD
    Cleveland Clinic Journal of Medicine March 2023, 90 (3) 161-164; DOI: https://doi.org/10.3949/ccjm.90a.22010

    A breakdown of benefits and drawbacks of sponsored genetic testing that clinicians can use to help patients make informed decisions.

  • What is the rationale for the laboratory workup for suspected pheochromocytomas and paragangliomas?
    Hiba Z. Hashmi, MD, Muhammad Arslan Arif Maan, MD and Laura LaFave, MD
    Cleveland Clinic Journal of Medicine March 2023, 90 (3) 150-153; DOI: https://doi.org/10.3949/ccjm.90a.20197

    The decision to test is best guided by clinical suspicion. Test results should be interpreted with careful consideration of how the samples were collected.

  • To repeat or not to repeat? Measuring bone mineral density during anti-resorptive therapy or a drug holiday
    Tayyab S. Khan, MD, Partha Sinha, MD, PhD and Harold Rosen, MD
    Cleveland Clinic Journal of Medicine March 2023, 90 (3) 173-180; DOI: https://doi.org/10.3949/ccjm.90a.22071

    The authors present evidence for and against monitoring bone mineral density in these patients, arguing against a one-size-fits-all approach.

  • Colovesical fistula in men with chronic urinary tract infection: A diagnostic challenge
    Risheng Xu, DO, Austin Vaughan, DO, Mitchell Fagan, DO, Dylan P. Schumacher, MD, Verra Wekullo, MD and Bruce Gehrke, MD
    Cleveland Clinic Journal of Medicine March 2023, 90 (3) 165-171; DOI: https://doi.org/10.3949/ccjm.90a.21060

    Most cases are in older men with diverticular disease, Crohn disease, cancer, or iatrogenic injury. Suspect it especially in these patients with UTI symptoms refractory to conventional treatments.

  • Our Peer-Reviewers For 2022
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine February 2023, 90 (2) 78;
  • A 50-year-old man presents with shortness of breath
    Kaylee Watson, MD, David Wolinsky, MD, Mauricio Velez, MD and David Snipelisky, MD, FACC
    Cleveland Clinic Journal of Medicine February 2023, 90 (2) 95-101; DOI: https://doi.org/10.3949/ccjm.90a.22021

    Red flags included low voltage, normal sinus rhythm, and Q waves on electrocardiography, a history of carpal tunnel syndrome, and evidence of renal dysfunction.

  • Resistant hypertension: A stepwise approach
    Resistant hypertension: A stepwise approach
    Jordana Yahr, DO, George Thomas, MD, Juan Calle, MD and Jonathan J. Taliercio, DO
    Cleveland Clinic Journal of Medicine February 2023, 90 (2) 115-125; DOI: https://doi.org/10.3949/ccjm.90a.22046

    The authors review the definition and prevalence of resistant hypertension and its diagnostic workup and management, including lifestyle modifications, drugs, and experimental therapies.

  • Vitamin D: A metabolic bone disease perspective
    Bruce Long, MD, FACR, BS Pharm
    Cleveland Clinic Journal of Medicine February 2023, 90 (2) 91-92; DOI: https://doi.org/10.3949/ccjm.90a.22086

    When checking levels, clinicians should keep in mind that vitamin D levels fluctuate by season and time of day, and that different laboratories may use different assays that yield different results.

  • What are the treatment options for myasthenia gravis if first-line agents fail?
    Christopher Zust, MD and John A. Morren, MD
    Cleveland Clinic Journal of Medicine February 2023, 90 (2) 81-84; DOI: https://doi.org/10.3949/ccjm.90a.22022

    From 5% to 20% of patients may have a suboptimal response or prohibitive adverse effects over a period of a few weeks to 3 months.

  • The constellation of vitamin D, the acute-phase response, and inflammation
    Maria J. Antonelli, MD, Irving Kushner, MD and Murray Epstein, MD, FASN, FACP
    Cleveland Clinic Journal of Medicine February 2023, 90 (2) 85-89; DOI: https://doi.org/10.3949/ccjm.90a.22048

    An astronomic increase in vitamin D testing and supplementation is happening in the absence of an evidence-based rationale.

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