Latest Articles

  • Psychedelic-assisted therapy: An overview for the internist
    Brian S. Barnett, MD, Erin E. Mauney, MD and Franklin King, MD
    Cleveland Clinic Journal of Medicine March 2025, 92 (3) 171-180; DOI: https://doi.org/10.3949/ccjm.92a.24032

    The authors review the potential effects, risks, and therapeutic applications of the psychedelic drugs MDMA (Ecstasy) and psilocybin, with a focus on MDMA-assisted therapy for posttraumatic stress disorder and psilocybin-assisted therapy for depression.

  • In Reply: Classic diabetic ketoacidosis and the euglycemic variant
    Adi E. Mehta, MD and Robert Zimmerman, MD
    Cleveland Clinic Journal of Medicine March 2025, 92 (3) 142-143; DOI: https://doi.org/10.3949/ccjm.92c.03003
  • Treating the thyroid: Trust the feedback loop
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine February 2025, 92 (2) 71-72; DOI: https://doi.org/10.3949/ccjm.92b.02025

    Studies show that, when testing to detect or monitor thyroid dysfunction, we order more free T3 and T4 levels than are necessary. We apparently should trust the thyroid-stimulating hormone feedback loop more than we do.

  • Vesicular pityriasis rosea
    Xiaobei Liu, MD, PhD, Lizhi Ma, MD, Peimei Zhou, MD, PhD and Tao Chen, MD, PhD
    Cleveland Clinic Journal of Medicine February 2025, 92 (2) 81-82; DOI: https://doi.org/10.3949/ccjm.92a.24004

    A 37-year-old man presented with a 9-day history of disseminated pruritic rash on his trunk and extremities.

  • Our Peer-Reviewers for 2024
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine February 2025, 92 (2) 79;
  • Which patients with presumed acute infectious diarrhea in an outpatient setting should undergo gastrointestinal pathogen panel testing?
    Brittany Jackson, MD, Sabrina Billings, MD, Dana M. Harris, MD, Jane Hata, PhD and Mary S. Hedges, MD
    Cleveland Clinic Journal of Medicine February 2025, 92 (2) 83-86; DOI: https://doi.org/10.3949/ccjm.92a.24084

    Use of a gastrointestinal pathogen panel is warranted in certain individuals, such as those with fever, visible blood in the stool, sepsis, or a compromised immune system.

  • Hypoglycemia after bariatric surgery: Management updates
    CME article
    Anira Iqbal, MD and Vinni Makin, MBBS, MD
    Cleveland Clinic Journal of Medicine February 2025, 92 (2) 103-108; DOI: https://doi.org/10.3949/ccjm.92a.24033

    The authors discuss how to differentiate post-bariatric surgery hypoglycemia from other causes of hypoglycemia, highlight the evolving role of continuous glucose monitors in detecting it, and summarize management options.

  • Respiratory virus season: Strategies for successful navigation
    Pooja Cerrato, PharmD, BCPS and Steven Mawhorter, MD, DTM&H
    Cleveland Clinic Journal of Medicine February 2025, 92 (2) 95-102; DOI: https://doi.org/10.3949/ccjm.92a.24103

    The authors review the burden, prevention, diagnosis, and treatment of influenza, COVID-19, and respiratory syncytial virus infection.

  • Wolff-Parkinson-White syndrome: Diagnostic and management strategies
    Masihullah Barat, MD, David Torres Barba, MD, PhD and Gordon Ho, MD
    Cleveland Clinic Journal of Medicine February 2025, 92 (2) 119-127; DOI: https://doi.org/10.3949/ccjm.92a.24059

    The challenge lies in managing those with the Wolff-Parkinson-White pattern on electrocardiogram but no symptoms.

  • Thyroid obstacle course: Many challenges from a single gland
    Timothy W. Bodnar, MD and Sima Saberi, MD
    Cleveland Clinic Journal of Medicine February 2025, 92 (2) 87-93; DOI: https://doi.org/10.3949/ccjm.92a.24076

    The patient presented to his primary care clinician for new irritability, anxiety, and insomnia. Laboratory testing revealed a low thyroid-stimulating hormone level.

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