Review

Genetics and hepatitis C: It’s good to be ‘CC’

Jose Mari Parungao, MD, Ibrahim A. Hanouneh, MD, Binu John, MD, Naim Alkhouri, MD and Nizar N. Zein, MD
Cleveland Clinic Journal of Medicine February 2015, 82 (2) 97-104; DOI: https://doi.org/10.3949/ccjm.82a.14004

ABSTRACT

The interleukin-28B (IL28B) gene contains a single-nucleotide polymorphism at location rs12979860 that affects both the natural history of hepatitis C virus infection and the patient’s response to treatment, particularly interferon-based regimens with or without protease inhibitors.

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