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II. Advances in Artificial Organs

Preclinical evaluation of a biolized temporary ventricular assist device

Ryohei Yozu, M.D., Leonard A. R. Golding, M.D., Gordon Jacobs, M.S., Shun Murabayashi, Ph.D., Hiroaki Harasaki, M.D., Ph.D., Raymond J. Kiraly, M.S. and Yukihiko Nosé, M.D., Ph.D.
Cleveland Clinic Journal of Medicine March 1984, 51 (1) 119-126;
Ryohei Yozu
Department of Artificial Organs, The Cleveland Clinic Foundation
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Leonard A. R. Golding
Department of Artificial Organs, The Cleveland Clinic Foundation
Department of Thoracic and Cardiovascular Surgery, The Cleveland Clinic Foundation
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Gordon Jacobs
Department of Artificial Organs, The Cleveland Clinic Foundation
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Shun Murabayashi
Department of Artificial Organs, The Cleveland Clinic Foundation
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Hiroaki Harasaki
Department of Artificial Organs, The Cleveland Clinic Foundation
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Raymond J. Kiraly
Department of Artificial Organs, The Cleveland Clinic Foundation
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Yukihiko Nosé
Department of Artificial Organs, The Cleveland Clinic Foundation
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ABSTRACT

An external clinical temporary ventricular assist device (VAD) has been developed with the use of our universal, multipurpose cardiac prosthesis with specially designed inflow and outflow cannulas. The cannulas allow flexibility in application of the VAD, which can access the vascular system via either the atrium or ventricle for inflow, and the aorta or pulmonary artery for outflow. A high-pressure pneumatic actuator activates the pusher-plate of the VAD. The clinical drive system for this VAD has complete redundancy and automatic switching to a backup system in the event of any component failure. Six VADs were tested in calves as a temporary left VAD before clinical use and functioned well.

Index terms
  • Artificial organs
  • Heart
  • mechanical
  • Prosthesis
  • cardiac
  • Received August 1983.
  • Accepted October 1983.
  • Copyright © 1984 The Cleveland Clinic Foundation. All Rights Reserved.
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Cleveland Clinic Journal of Medicine: 51 (1)
Cleveland Clinic Journal of Medicine
Vol. 51, Issue 1
20 Mar 1984
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Preclinical evaluation of a biolized temporary ventricular assist device
Ryohei Yozu, Leonard A. R. Golding, Gordon Jacobs, Shun Murabayashi, Hiroaki Harasaki, Raymond J. Kiraly, Yukihiko Nosé
Cleveland Clinic Journal of Medicine Mar 1984, 51 (1) 119-126;

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Preclinical evaluation of a biolized temporary ventricular assist device
Ryohei Yozu, Leonard A. R. Golding, Gordon Jacobs, Shun Murabayashi, Hiroaki Harasaki, Raymond J. Kiraly, Yukihiko Nosé
Cleveland Clinic Journal of Medicine Mar 1984, 51 (1) 119-126;
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Show more II. Advances in Artificial Organs

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Keywords

  • Artificial organs
  • Heart
  • Mechanical
  • Prosthesis
  • cardiac

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