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I. Epilepsy: Current Concepts in Diagnosis and Treatment

Status epilepticus

Richard J. Lederman, M.D., Ph.D.
Cleveland Clinic Journal of Medicine June 1984, 51 (2) 261-266;
Richard J. Lederman
Department of Neurology, The Cleveland Clinic Foundation
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ABSTRACT

Status epilepticus (SE), defined as clinical or electrical seizures continuing for at least 30 minutes, occurs in a minority of patients with epilepsy and is more common in symptomatic than in idiopathic forms. In adults, brain tumor, trauma, and stroke account for a substantial proportion of cases, whereas in children, various infectious processes, toxic or metabolic disorders, and chronic encephalopathies may be found. SE is often precipitated by sudden withdrawal of anticonvulsant drugs or intercurrent infection. Prolonged seizures lead to a series of metabolic derangements which may subsequently cause neuronal damage. Therapy aimed at preventing this sequence of events includes general measures, such as ensuring sufficient oxygenation, maintaining adequate blood pressure, and preventing hyperthermia or hypoglycemia. Specific anticonvulsant drug therapy is reviewed, including recommended doses, mode and rate of administration, and potential hazards.

Index terms
  • Anticonvulsants
  • Epilepsy
  • Status epilepticus
  • Received October 1983.
  • Accepted October 1983.
  • Copyright © 1984 The Cleveland Clinic Foundation. All Rights Reserved.

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Cleveland Clinic Journal of Medicine: 51 (2)
Cleveland Clinic Journal of Medicine
Vol. 51, Issue 2
20 Jun 1984
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Status epilepticus
Richard J. Lederman
Cleveland Clinic Journal of Medicine Jun 1984, 51 (2) 261-266;

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Status epilepticus
Richard J. Lederman
Cleveland Clinic Journal of Medicine Jun 1984, 51 (2) 261-266;
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More in this TOC Section

I. Epilepsy: Current Concepts in Diagnosis and Treatment

  • Complex partial seizures of childhood onset: a clinical and encephalography: study
  • Surgical techniques for relief from seizures
  • Infantile spasms
Show more I. Epilepsy: Current Concepts in Diagnosis and Treatment

Contributions

  • Complex partial seizures of childhood onset: a clinical and encephalography: study
  • Surgical techniques for relief from seizures
  • Infantile spasms
Show more Contributions

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Keywords

  • Anticonvulsants
  • Epilepsy
  • Status epilepticus

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