Corpus callosum section for seizure control: rationale and review of experimental and clinical data

ABSTRACT

This contribution reviews several physiological and clinical prerequisites for consideration of corpus callosotomy for seizure control. Although there are experimental data suggesting that this procedure would fail to measurably improve an uncontrolled seizure disorder, initial clinical experience with the procedure appears to be generally favorable. More defined case selection and longer follow-up are needed to fully evaluate its effectiveness. An outline of selection criteria and postoperative evaluation concludes the contribution.