Skip to main content

Main menu

  • Home
  • Content
    • Current Issue
    • Ahead of Print
    • Past Issues
    • Supplements
    • Article Type
  • Specialty
    • Articles by Specialty
  • CME/MOC
    • Articles
    • Calendar
  • Info For
    • Manuscript Submission
    • Authors & Reviewers
    • Subscriptions
    • About CCJM
    • Contact Us
    • Media Kit
  • Conversations with Leaders
  • Conference Coverage
    • Kidney Week 2024
    • CHEST 2024
    • ACR Convergence 2023
    • Kidney Week 2023
    • ObesityWeek 2023
    • IDWeek 2023
    • CHEST 2023
    • MDS 2023
    • IAS 2023
    • ACP 2023
    • AAN 2023
    • ACC / WCC 2023
    • AAAAI Meeting 2023
    • ACR Convergence 2022
    • Kidney Week 2022
    • AIDS 2022
  • Other Publications
    • www.clevelandclinic.org

User menu

  • Register
  • Log in

Search

  • Advanced search
Cleveland Clinic Journal of Medicine
  • Other Publications
    • www.clevelandclinic.org
  • Register
  • Log in
Cleveland Clinic Journal of Medicine

Advanced Search

  • Home
  • Content
    • Current Issue
    • Ahead of Print
    • Past Issues
    • Supplements
    • Article Type
  • Specialty
    • Articles by Specialty
  • CME/MOC
    • Articles
    • Calendar
  • Info For
    • Manuscript Submission
    • Authors & Reviewers
    • Subscriptions
    • About CCJM
    • Contact Us
    • Media Kit
  • Conversations with Leaders
  • Conference Coverage
    • Kidney Week 2024
    • CHEST 2024
    • ACR Convergence 2023
    • Kidney Week 2023
    • ObesityWeek 2023
    • IDWeek 2023
    • CHEST 2023
    • MDS 2023
    • IAS 2023
    • ACP 2023
    • AAN 2023
    • ACC / WCC 2023
    • AAAAI Meeting 2023
    • ACR Convergence 2022
    • Kidney Week 2022
    • AIDS 2022
Contributions

Captopril renography for the detection of renovascular hypertension

A preliminary report

Joseph V. Nally, MD, Bharat K. Gupta, MD, Harry S. Clarke, MD, PHD, James T. Higgins, MD, William J. Potvin, PHD and Michael L. Gross, MD
Cleveland Clinic Journal of Medicine July 1988, 55 (4) 311-318;
Joseph V. Nally Jr.
Department of Hypertension and Nephrology, The Cleveland Clinic Foundation, Cleveland, Ohio
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Bharat K. Gupta
Department of Medicine and Radiology, Medical College of Ohio, Toledo, Ohio
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Harry S. Clarke Jr.
Department of Medicine and Radiology, Medical College of Ohio, Toledo, Ohio
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
James T. Higgins Jr.
Department of Medicine and Radiology, Medical College of Ohio, Toledo, Ohio
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
William J. Potvin
Department of Medicine and Radiology, Medical College of Ohio, Toledo, Ohio
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Michael L. Gross
Department of Medicine and Radiology, Medical College of Ohio, Toledo, Ohio
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Info & Metrics
  • PDF
Loading

ABSTRACT

The effect of a provocative challenge with an angiotensin-converting enzyme inhibitor (captopril) upon technetium-99m-labeled diethylene triaminepentaacetic acid (Tc-99m-labeled DTPA) and iodohippurate sodium 1-131 (1-131 Hippuran) renograms was studied in a group of 16 selected hypertensive patients. The patients were categorized as having either renal artery stenosis (RAS, n= 11) or essential hypertension (EHT, n=5) based upon renal angiographic findings. In patients with RAS, captopril altered the time-activity curves of the stenotic kidney(s) of both radionuclide studies and improved the diagnostic sensitivity. In patients with EHT, captopril did not alter the radionuclide studies. Converting-enzyme inhibition coupled with noninvasive radionuclide studies of the renovascular bed offers promise in improving the sensitivity and specificity for detecting hemodynamically significant RAS in the hypertensive population.

INDEX TERMS
  • Captopril
  • Hypertension
  • Renal
  • Radioisotope Renography
  • Received July 1987.
  • Accepted September 1987.
  • Copyright © 1988 The Cleveland Clinic Foundation. All Rights Reserved.
PreviousNext
Back to top

In this issue

Cleveland Clinic Journal of Medicine: 55 (4)
Cleveland Clinic Journal of Medicine
Vol. 55, Issue 4
1 Jul 1988
  • Table of Contents
  • Table of Contents (PDF)
  • Index by author
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on Cleveland Clinic Journal of Medicine.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Captopril renography for the detection of renovascular hypertension
(Your Name) has sent you a message from Cleveland Clinic Journal of Medicine
(Your Name) thought you would like to see the Cleveland Clinic Journal of Medicine web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Captopril renography for the detection of renovascular hypertension
Joseph V. Nally, Bharat K. Gupta, Harry S. Clarke, James T. Higgins, William J. Potvin, Michael L. Gross
Cleveland Clinic Journal of Medicine Jul 1988, 55 (4) 311-318;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Captopril renography for the detection of renovascular hypertension
Joseph V. Nally, Bharat K. Gupta, Harry S. Clarke, James T. Higgins, William J. Potvin, Michael L. Gross
Cleveland Clinic Journal of Medicine Jul 1988, 55 (4) 311-318;
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Linkedin Share Button

Jump to section

  • Article
  • Info & Metrics
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

  • Panic disorder and social phobia: Current treatments and new strategies
  • Anticonvulsants for neuropathic pain and detoxification
  • Bipolar disorder: Current treatments and new strategies
Show more Contributions

Similar Articles

Keywords

  • Captopril
  • Hypertension
  • renal
  • Radioisotope Renography

Navigate

  • Current Issue
  • Past Issues
  • Supplements
  • Article Type
  • Specialty
  • CME/MOC Articles
  • CME/MOC Calendar
  • Media Kit

Authors & Reviewers

  • Manuscript Submission
  • Authors & Reviewers
  • Subscriptions
  • About CCJM
  • Contact Us
  • Cleveland Clinic Center for Continuing Education
  • Consult QD

Share your suggestions!

Copyright © 2025 The Cleveland Clinic Foundation. All rights reserved. The information provided is for educational purposes only. Use of this website is subject to the website terms of use and privacy policy. 

Powered by HighWire