ABSTRACT
Basic research is bringing a much-needed infusion of optimism and urgency to the clinical diagnosis and treatment of Alzheimer disease. Some of its risk factors may be modifiable, and although current drugs offer only modest benefit, true disease-modifying drugs are on the horizon. This review is aimed at primary care physicians, who are the first clinicians to see patients with Alzheimer disease and are responsible for their ongoing care throughout the course of their dementia.
Footnotes
↵a Dr. Salloway has received research support and honoraria from and has served as a consultant for Johnson and Johnson, Eisai, Pfizer, Forest, and Myriad Pharmaceuticals companies. He receives research support from Elan, Neurochem, and Cephalon companies and the National Institutes of Health. He is on the speaker panel for Novartis and Athena Diagnostics and has served as a consultant for sanofiaventis and Merck companies.
↵b Dr. Correia has received research support from the Alzheimer’s Association and the Rhode Island Foundation.
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