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Review

The FREEDOM trial: In appropriate patients with diabetes and multivessel coronary artery disease, CABG beats PCI

Bhuvnesh Aggarwal, MD, Sachin S. Goel, MD, Joseph F. Sabik, MD and Mehdi H. Shishehbor, DO, MPH, PhD
Cleveland Clinic Journal of Medicine August 2013, 80 (8) 515-523; DOI: https://doi.org/10.3949/ccjm.80a.13030
Bhuvnesh Aggarwal
Department of Internal Medicine, Cleveland Clinic
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Sachin S. Goel
Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic
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Joseph F. Sabik
Chair, Department of Thoracic and Cardiovascular Surgery; Staff, Critical Care Center, Heart and Vascular Institute, Cleveland Clinic; and Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
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Mehdi H. Shishehbor
Director, Endovascular Services, Interventional Cardiology and Vascular Medicine, Heart and Vascular Institute, Cleveland Clinic
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  • For correspondence: shishem@ccf.org
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ABSTRACT

The Future Revascularization Evaluation in Patients With Diabetes Mellitus: Optimal Management of Multivessel Disease (FREEDOM) trial (N Engl J Med 2012; 367:2375–2384) was designed to resolve the long-standing debate over the optimal revascularization strategy in patients with diabetes mellitus and multivessel coronary artery disease. At a median follow-up of 3.8 years, the incidence of the primary outcome (a composite of death, myocardial infarction, and stroke) was significantly lower with bypass surgery than with percutaneous intervention.

  • Copyright © 2013 The Cleveland Clinic Foundation. All Rights Reserved.
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Cleveland Clinic Journal of Medicine: 80 (8)
Cleveland Clinic Journal of Medicine
Vol. 80, Issue 8
1 Aug 2013
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The FREEDOM trial: In appropriate patients with diabetes and multivessel coronary artery disease, CABG beats PCI
Bhuvnesh Aggarwal, Sachin S. Goel, Joseph F. Sabik, Mehdi H. Shishehbor
Cleveland Clinic Journal of Medicine Aug 2013, 80 (8) 515-523; DOI: 10.3949/ccjm.80a.13030

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The FREEDOM trial: In appropriate patients with diabetes and multivessel coronary artery disease, CABG beats PCI
Bhuvnesh Aggarwal, Sachin S. Goel, Joseph F. Sabik, Mehdi H. Shishehbor
Cleveland Clinic Journal of Medicine Aug 2013, 80 (8) 515-523; DOI: 10.3949/ccjm.80a.13030
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