When patients on target-specific oral anticoagulants need surgery

  • Cleveland Clinic Journal of Medicine
  • October 2014,
  • 81
  • (10)
  • 629-639;
  • DOI: https://doi.org/10.3949/ccjm.81a.13168

ABSTRACT

The target-specific oral anticoagulants (TSOACs), eg, dabigatran, rivaroxaban, and apixaban, are changing the way we manage thromboembolic disease. At the same time, many clinicians wonder how best to manage TSOAC therapy when patients need surgery. An in-depth understanding of these drugs is essential to minimize the risk of bleeding and thrombosis perioperatively.

Footnotes

  • ↵* Dr. Trujillo has disclosed consulting for Boehringer Ingelheim, Janssen Pharmaceuticals, and Pfizer/Bristol-Myers Squibb.

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