Table of Contents
From the Editor
- To dream the maybe possible dream: A breast cancer vaccine
The work is in an extremely preliminary phase, but the concept is an active area of research worth keeping tabs on.
Smart Testing
- Should all patients have a resting 12-lead ECG before elective noncardiac surgery?
If the risk is low, an ECG could unnecessarily delay surgery, drive up costs, trigger further testing, and increase anxiety.
The Clinical Picture
- Terry nails in a patient with chronic alcoholic liver disease
His fingernails had a distal thin brown-pink transverse band, a white nail bed, and no lunula.
Medical Grand Rounds
- Bench-to-bedside challenges in developing immune protection against breast cancer
A vaccine against breast cancer is being developed. Here, the author explains the principles and challenges.
- Keeping up with immunizations for adults
Flu, tetanus, measles, mumps, rubella, varicella, hepatitis A and B, human papillomavirus, zoster, pneumonia, and meningitis.
Review
- Managing snoring: When to consider surgery
If conservative measures fail, a variety of surgical procedures are designed to keep the airway open during sleep.
- Diabetes therapy and cancer risk: Where do we stand when treating patients?
Several classes of diabetes drugs are under scrutiny for potentially promoting cancer in a population already at risk.
When patients on target-specific oral anticoagulants need surgeryUntil evidence-based guidelines are developed, clinicians will have to apply their knowledge of pharmacology.
Departments
- Why is metformin contraindicated in chronic kidney disease? (May 2014)
A reader comments on why metformin is contraindicated in chronic kidney disease, which was mentioned by Sakhuja et al (Cleve Clin J Med 2014; 81:289–299).
