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The Clinical Picture

A broken pacemaker lead in a 69-year-old woman

Belal Kaseer, MD, Mhd Yassin Al Mouslmani, MD, David S. Hirsh, MD and Muhammad Hammadah, MD
Cleveland Clinic Journal of Medicine May 2017, 84 (5) 346-347; DOI: https://doi.org/10.3949/ccjm.84a.16075
Belal Kaseer
Dnipropetrovsk Medical Academy, Dnipropetrovsk, Ukraine
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Mhd Yassin Al Mouslmani
Lincoln Medical and Mental Health Center, New York, NY
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David S. Hirsh
Assistant Professor of Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, GA
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Muhammad Hammadah
Department of Medicine, Division of Cardiology, Emory University School of Medicine, Atlanta, GA
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A 69-year-old woman presented with fatigue, cough, and lightheadedness. She had a history of atrial fibrillation and complete heart block, for which she had a pacemaker (dual-pacing, dual-sensing, dual-response, and rate-adaptive mode) inserted in 2005. Her heart rate was 30 beats per minute.

A chest radiograph showed a fractured right ventricular pacemaker lead (Figure 1). Electrocardiography showed sinus rhythm with a high-grade atrioventricular block (Figure 2). Pacemaker interrogation confirmed the diagnosis of lead fracture. A new lead was placed, and the old lead was abandoned.

FIGURE 1
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FIGURE 1

Posterior-anterior chest radiograph showed discontinuity of a lead wire, consistent with complete lead fracture.

HOW LEADS BREAK

The rate of lead fracture ranges from 0.1% to 4.2% per patient-year, and the annual failure rate increases progressively with time after implantation.1,2

Extrinsic pressure on the lead can eventually break it. This can happen between the first rib and clavicle, in “subclavian crush” injury, or with any anatomical abnormality that narrows the thoracic outlet. Typically, classic subclavian crush results from entrapment of the pacemaker leads by the subclavius muscle or the costoclavicular ligament as the lead follows the needle course of the antecedent access puncture of the subclavian vein. This results in intermittent flexing of the lead and potential lead fracture3 and was likely the cause of lead fracture in our patient.

The risk of fracture is higher in patients under the age of 50, those who perform intense physical activity, women, and patients with greater left ventricular ejection fraction.4,5 Certain leads are prone to fracture due to design flaws. One of these was the Medtronic Sprint Fidelis cardioverter defibrillator lead, which was recalled in 2007.5

DETECTING LEAD FRACTURE

Symptoms of lead fracture vary, depending on the patient’s pacemaker-dependency and on the degree of loss of capture (ie, the degree to which the heart fails to respond to the pacemaker’s signals), and may include lightheadedness, syncope, and extracardiac stimulation.

The electrical integrity of a lead can be tested by measuring the circuit impedance, which normally ranges from 300 to 1,000 ohms.6 An insulation failure results in very low impedance, while a disrupted circuit due to lead fracture commonly causes a sudden rather than gradual increase in impedance.6

FIGURE 2
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FIGURE 2

The patient’s electrocardiogram showed sinus rhythm, high-grade atrioventricular block, reflected by the atrioventricular dissociation with intermittent conduction (asterisk), and pacemaker spikes (arrows) with loss of capture, reflected by the absence of QRS waves following the pacemaker spikes.

Simple imaging studies such as chest radiography or fluoroscopy may establish the diagnosis of lead fracture. One should carefully trace every lead along its entire course and look for any conductor discontinuity, kinks, or sharp bends.6

REMOVE THE OLD LEAD, OR LEAVE IT IN PLACE?

The treatment for lead fracture is usually to put in a new lead, with or without extracting the old one.

In view of the potential complications of lead removal such as cardiac perforation or vascular tear, lead abandonment with placement of a new lead may be performed.7 There are no controlled clinical studies comparing lead abandonment vs lead extraction.8 However, extraction is currently recommended only in patients in whom the old lead causes life-threatening arrhythmias, interferes with the operation of implanted cardiac devices, interferes with radiation therapy or needed surgery, or, due to its design or failure, poses an immediate threat to the patient if left in place.7 Lead removal is reasonable in patients who require specific imaging studies such as magnetic resonance imaging with no available imaging alternative for the diagnosis.7

In our patient, a new lead was placed without removing the fractured lead, with no complications. Afterward, the patient’s heart rhythm was observed to be appropriately paced, and she was discharged home the following day.

  • Copyright © 2017 The Cleveland Clinic Foundation. All Rights Reserved.

REFERENCES

  1. ↵
    1. Alt E,
    2. Völker R,
    3. Blömer H
    . Lead fracture in pacemaker patients. Thorac Cardiovasc Surg 1987; 35:101–104.
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    1. Kleemann T,
    2. Becker T,
    3. Doenges K,
    4. et al
    . Annual rate of transvenous defibrillation lead defects in implantable cardioverter-defibrillators over a period of > 10 years. Circulation 2007; 115:2474–2480.
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    1. Magney JE,
    2. Flynn DM,
    3. Parsons JA,
    4. et al
    . Anatomical mechanisms explaining damage to pacemaker leads, defibrillator leads, and failure of central venous catheters adjacent to the sternoclavicular joint. Pacing Clin Electrophysiol 1993; 16:445–457.
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    1. Farwell D,
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    4. Gollob MH,
    5. Birnie DH
    . Accelerating risk of Fidelis lead fracture. Heart Rhythm 2008; 5:1375–1379.
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    1. Morrison TB,
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    3. Hodge DO,
    4. et al
    . Risk factors for implantable defibrillator lead fracture in a recalled and a nonrecalled lead. J Cardiovasc Electrophysiol 2010; 21:671–677.
    OpenUrlCrossRefPubMed
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    1. Swerdlow CD,
    2. Ellenbogen KA
    . Implantable cardioverter-defibrillator leads: design, diagnostics, and management. Circulation 2013; 128:2062–2071.
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    1. Wilkoff BL,
    2. Love CJ,
    3. Byrd CL,
    4. et al
    5. Heart Rhythm Society
    6. American Heart Association
    . Transvenous lead extraction: Heart Rhythm Society expert consensus on facilities, training, indications, and patient management: this document was endorsed by the American Heart Association (AHA). Heart Rhythm 2009; 6:1085–1104.
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    1. Maytin M,
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    3. Henrikson CA
    . Lead extraction is preferred for lead revisions and system upgrades: when less is more. Circ Arrhythm Electrophysiol 2010; 3:413–424.
    OpenUrlFREE Full Text
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Cleveland Clinic Journal of Medicine: 84 (5)
Cleveland Clinic Journal of Medicine
Vol. 84, Issue 5
1 May 2017
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A broken pacemaker lead in a 69-year-old woman
Belal Kaseer, Mhd Yassin Al Mouslmani, David S. Hirsh, Muhammad Hammadah
Cleveland Clinic Journal of Medicine May 2017, 84 (5) 346-347; DOI: 10.3949/ccjm.84a.16075

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A broken pacemaker lead in a 69-year-old woman
Belal Kaseer, Mhd Yassin Al Mouslmani, David S. Hirsh, Muhammad Hammadah
Cleveland Clinic Journal of Medicine May 2017, 84 (5) 346-347; DOI: 10.3949/ccjm.84a.16075
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