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Cleveland Clinic Journal of Medicine
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Cleveland Clinic Journal of Medicine

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Cardiology

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    Should I start anticoagulation in my patient newly diagnosed with pulmonary hypertension?
    Tark Abou-Elmagd, MD, MSc, MBBCh and Shraddha Narechania, MD
    Cleveland Clinic Journal of Medicine June 2025, 92 (6) 339-343; DOI: https://doi.org/10.3949/ccjm.92a.24083

    The decision hinges on the subtype of pulmonary hypertension the patient has.

  • You have access
    Nitrogen: The unsung hero of vascular physiology
    Adam J. Brown, MD
    Cleveland Clinic Journal of Medicine June 2025, 92 (6) 344-346; DOI: https://doi.org/10.3949/ccjm.92a.24120

    The seventh element on the periodic table—nitrogen—may not come to mind often in day-to-day medical practice, but it is more exciting than you might think.

  • You have access
    My adult patient’s hypercholesterolemia is not responding to statins—what’s next?
    Faaiq N. Aslam, MD, Mohamed G. Ibrahim, DO and Razvan Chirila, MD
    Cleveland Clinic Journal of Medicine June 2025, 92 (6) 347-351; DOI: https://doi.org/10.3949/ccjm.92a.24117

    Further investigation is needed when patients do not meet their target low-density lipoprotein cholesterol levels with statin therapy alone.

  • You have access
    Direct oral anticoagulants: Challenging prescribing scenarios in everyday practice
    CME article
    Syed Bukhari, MD, MHA, Mohamed Ghoweba, MD, Syed Zamrak Khan, MD, Ammar Saati, MD and Marcelo Gomes, MD
    Cleveland Clinic Journal of Medicine June 2025, 92 (6) 353-361; DOI: https://doi.org/10.3949/ccjm.92a.24061

    Preapproval trials of direct oral anticoagulants excluded patients with extreme body weight and advanced kidney and liver disease and those who had undergone bariatric surgery. Cautious decision-making in these patients is warranted.

  • You have access
    High-output heart failure from arteriovenous dialysis access: A structured approach to diagnosis and management
    Maximilian C. Volk, DO, Bianca Honnekeri, MD, Joanna Ghobrial, MD, Mazen Hanna, MD, Sanjeeb Bhattacharya, MD, Lee Kirksey, MD, J. Emanuel Finet, MD and Heba Wassif, MD, MPH
    Cleveland Clinic Journal of Medicine June 2025, 92 (6) 362-371; DOI: https://doi.org/10.3949/ccjm.92a.24114

    Arteriovenous high-output heart failure is likely underdiagnosed because many clinicians are uncertain about when and how to evaluate for it.

  • You have access
    Do I need to treat supine hypertension in my hospitalized patient?
    Katherine Sherman, MD and Robert Lichtenberg, MD
    Cleveland Clinic Journal of Medicine May 2025, 92 (5) 285-289; DOI: https://doi.org/10.3949/ccjm.92a.24092

    Inpatients with an elevated supine blood pressure should be evaluated for orthostatic changes before treatment is considered.

  • You have access
    New atrial fibrillation guideline: Modify risk, control rhythm, prevent progression
    CME article
    Laura A. Campbell, MD, Jessica P. Ammon, DO, Rachana Kombathula, MD, Naa’irah Muhammad, MD and Christopher D. Jackson, MD
    Cleveland Clinic Journal of Medicine May 2025, 92 (5) 291-296; DOI: https://doi.org/10.3949/ccjm.92a.24067

    Key updates in the new American guideline include recommendations for aggressive lifestyle and risk-factor modifications, annual assessment of thromboembolic risk, and early rhythm control.

  • You have access
    The beat goes on: Highlights from the new American and European A-fib guidelines
    Sandra Howell, MBBS, MEd, MSc, MPhil, Alphonsus Liew, MBBS and Christopher Aldo Rinaldi, MD
    Cleveland Clinic Journal of Medicine May 2025, 92 (5) 297-300; DOI: https://doi.org/10.3949/ccjm.92a.25030

    The authors discuss and compare the latest atrial fibrillation guidelines from American and European medical societies.

  • Managing right ventricular failure in the setting of pulmonary embolism
    You have access
    Managing right ventricular failure in the setting of pulmonary embolism
    Sharmeen Sorathia, MD, Anibelky Almanzar, MD, Abhishek Bhandiwad, MD and Phoo Pwint Nandar, MD
    Cleveland Clinic Journal of Medicine May 2025, 92 (5) 301-309; DOI: https://doi.org/10.3949/ccjm.92a.24069

    The authors review current management strategies, including medical, percutaneous interventional, and surgical options, and discuss recent advances in the field.

  • You have access
    Prolonged venous filling time and dependent rubor in a patient with peripheral artery disease
    Scott L. Hagan, MD and Jeffrey W. Redinger, MD
    Cleveland Clinic Journal of Medicine April 2025, 92 (4) 205-206; DOI: https://doi.org/10.3949/ccjm.92a.24056

    Physical examination in a man who presented with foot pain revealed absent bilateral posterior tibial and dorsalis pedis pulses and dusky erythema of both feet.

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