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Review

Functional dyspepsia: How to manage the burn and the bloat

Scott Gabbard, MD and Nina Vijayvargiya, BS
Cleveland Clinic Journal of Medicine May 2024, 91 (5) 301-307; DOI: https://doi.org/10.3949/ccjm.91a.23062
Scott Gabbard
Department of Gastroenterology, Hepatology, and Nutrition, Digestive Disease Institute, Cleveland Clinic, Cleveland, OH; Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
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Nina Vijayvargiya
Emory University, Atlanta, GA
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ABSTRACT

Functional dyspepsia is defined as persistent symptoms of postprandial bloating, early satiety, or pain in the center of the upper abdomen, without findings on upper endoscopy such as peptic ulcer disease to explain these symptoms. It is common, affecting up to 30% of the global population, but it often goes undiagnosed for years. There are 2 subtypes: epigastric pain syndrome (burning and pain) and postprandial distress syndrome (bloating and satiety). The authors discuss how to diagnose and treat both subtypes.

  • Copyright © 2024 The Cleveland Clinic Foundation. All Rights Reserved.
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  1. 17935-scott-gabbardScott Gabbard, MD⇑
  1. Department of Gastroenterology, Hepatology, and Nutrition, Digestive Disease Institute, Cleveland Clinic, Cleveland, OH; Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
  1. Address:
    Scott Gabbard, MD, Department of Gastroenterology, Hepatology, and Nutrition, A31, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195; gabbars{at}ccf.org
  1. Nina Vijayvargiya, BS
  1. Emory University, Atlanta, GA

ABSTRACT

Functional dyspepsia is defined as persistent symptoms of postprandial bloating, early satiety, or pain in the center of the upper abdomen, without findings on upper endoscopy such as peptic ulcer disease to explain these symptoms. It is common, affecting up to 30% of the global population, but it often goes undiagnosed for years. There are 2 subtypes: epigastric pain syndrome (burning and pain) and postprandial distress syndrome (bloating and satiety). The authors discuss how to diagnose and treat both subtypes.

  • Copyright © 2024 The Cleveland Clinic Foundation. All Rights Reserved.
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Cleveland Clinic Journal of Medicine: 91 (5)
Cleveland Clinic Journal of Medicine
Vol. 91, Issue 5
1 May 2024
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Functional dyspepsia: How to manage the burn and the bloat
Scott Gabbard, Nina Vijayvargiya
Cleveland Clinic Journal of Medicine May 2024, 91 (5) 301-307; DOI: 10.3949/ccjm.91a.23062

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Functional dyspepsia: How to manage the burn and the bloat
Scott Gabbard, Nina Vijayvargiya
Cleveland Clinic Journal of Medicine May 2024, 91 (5) 301-307; DOI: 10.3949/ccjm.91a.23062
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  • Article
    • ABSTRACT
    • TWO CATEGORIES
    • FUNCTIONAL DYSPEPSIA VS IRRITABLE BOWEL SYNDROME
    • PATHOPHYSIOLOGY
    • CRITERIA FOR DIAGNOSIS
    • SYMPTOMS CAN WAX AND WANE
    • TREATMENTS ARE ALL OFF-LABEL
    • GENERAL MANAGEMENT PRINCIPLES
    • CASE FOLLOW-UP: IMPROVEMENT WITH BUSPIRONE
    • EDUCATIONAL SOURCES
    • DISCLOSURES
    • REFERENCES
  • Figures & Data
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