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COVID-19 Curbside Consults

Update to coagulopathy in COVID-19: Manifestations and management

Simon R. Mucha, MD, Siddharth Dugar, MD, Keith McCrae, MD, Douglas Joseph, DO, John Bartholomew, MD, Gretchen L. Sacha, PharmD, RPh, BCCCP and Michael Militello, PharmD, RPh, BCPS
Cleveland Clinic Journal of Medicine June 2021, DOI: https://doi.org/10.3949/ccjm.87a.ccc024-up
Simon R. Mucha
Critical Care Medicine, Respiratory Institute, Cleveland Clinic; Clinical Instructor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
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Siddharth Dugar
Pulmonary Medicine, Cleveland Clinic; Clinical Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
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Keith McCrae
Hematology and Medical Oncology, and Cellular and Molecular Medicine, Cleveland Clinic; Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
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Douglas Joseph
Cardiovascular Medicine, Cleveland Clinic; Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
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John Bartholomew
Cardiovascular Medicine, Cleveland Clinic; Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
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  • For correspondence: [email protected]
Gretchen L. Sacha
Inpatient Pharmacy, Cleveland Clinic
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Michael Militello
Inpatient Pharmacy, Cleveland Clinic
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Article Information

DOI 
https://doi.org/10.3949/ccjm.87a.ccc024-up
PubMed 
33323363

Published By 
Cleveland Clinic Journal of Medicine
Print ISSN 
0891-1150
Online ISSN 
1939-2869
History 
  • Published online June 2, 2021.

Article Versions

  • previous version (December 15, 2020 - 11:42).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2020 The Cleveland Clinic Foundation. All Rights Reserved.

Author Information

  1. Simon R. Mucha, MD
  1. Critical Care Medicine, Respiratory Institute, Cleveland Clinic; Clinical Instructor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
  1. Siddharth Dugar, MD
  1. Pulmonary Medicine, Cleveland Clinic; Clinical Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
  1. Keith McCrae, MD
  1. Hematology and Medical Oncology, and Cellular and Molecular Medicine, Cleveland Clinic; Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
  1. Douglas Joseph, DO
  1. Cardiovascular Medicine, Cleveland Clinic; Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
  1. John Bartholomew, MD⇑
  1. Cardiovascular Medicine, Cleveland Clinic; Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
  1. Address:
    John R. Bartholomew, MD, Cardiovascular Medicine, ST20, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195; barthoj{at}ccf.org
  1. Gretchen L. Sacha, PharmD, RPh, BCCCP
  1. Inpatient Pharmacy, Cleveland Clinic
  1. Michael Militello, PharmD, RPh, BCPS
  1. Inpatient Pharmacy, Cleveland Clinic
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Cleveland Clinic Journal of Medicine: 92 (5)
Cleveland Clinic Journal of Medicine
Vol. 92, Issue 5
1 May 2025
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Update to coagulopathy in COVID-19: Manifestations and management
Simon R. Mucha, Siddharth Dugar, Keith McCrae, Douglas Joseph, John Bartholomew, Gretchen L. Sacha, Michael Militello
Cleveland Clinic Journal of Medicine Jun 2021, DOI: 10.3949/ccjm.87a.ccc024-up

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Update to coagulopathy in COVID-19: Manifestations and management
Simon R. Mucha, Siddharth Dugar, Keith McCrae, Douglas Joseph, John Bartholomew, Gretchen L. Sacha, Michael Militello
Cleveland Clinic Journal of Medicine Jun 2021, DOI: 10.3949/ccjm.87a.ccc024-up
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  • Article
    • ABSTRACT
    • INTRODUCTION
    • A HIGHLY THROMBOTIC STATE
    • LABORATORY FINDINGS: ELEVATED D-DIMER
    • SEVERE LUNG DAMAGE FROM INFLAMMATION, THROMBOSIS
    • PATHOPHYSIOLOGY: INFLAMMATION PROMOTES THROMBOSIS
    • OUR MANAGEMENT APPROACH
    • DISCLOSURES
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