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Case Report

The effects of steroid therapy on pulmonary hypertension secondary to fibrosing mediastinitis

Edward M. Cordasco, DO, Muzaffar Ahmad, MD, Atul Mehta, MD and Felipe Rubio, MD
Cleveland Clinic Journal of Medicine October 1990, 57 (7) 647-652;
Edward M. Cordasco Jr
Department of Pulmonary Disease, The Cleveland Clinic Foundation
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Muzaffar Ahmad
Department of Pulmonary Disease, The Cleveland Clinic Foundation
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Atul Mehta
Department of Pulmonary Disease, The Cleveland Clinic Foundation
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Felipe Rubio
Kettering Medical Center, Kettering, Ohio.
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ABSTRACT

Mediastinal fibrosis, a rare cause of pulmonary hypertension, may produce cough, dyspnea, and hemoptysis. Steroid therapy has been suggested for individuals with progressive symptoms, but data demonstrating the efficacy of such therapy are lacking. We present a case of pulmonary hypertension secondary to fibrosing mediastinitis. Hemodynamic and scintigraphic studies performed before and after a trial of corticosteroid therapy were unable to demonstrate any therapeutic benefit from the corticosteroids. In order to achieve better use of steroids for the treatment of this disease, we suggest that similar determinations be made on other patients with mediastinal fibrosis who receive such treatment.

INDEX TERM
  • Pulmonary Hypertension
  • Copyright © 1990 The Cleveland Clinic Foundation. All Rights Reserved.
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Cleveland Clinic Journal of Medicine: 57 (7)
Cleveland Clinic Journal of Medicine
Vol. 57, Issue 7
1 Oct 1990
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The effects of steroid therapy on pulmonary hypertension secondary to fibrosing mediastinitis
Edward M. Cordasco, Muzaffar Ahmad, Atul Mehta, Felipe Rubio
Cleveland Clinic Journal of Medicine Oct 1990, 57 (7) 647-652;

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The effects of steroid therapy on pulmonary hypertension secondary to fibrosing mediastinitis
Edward M. Cordasco, Muzaffar Ahmad, Atul Mehta, Felipe Rubio
Cleveland Clinic Journal of Medicine Oct 1990, 57 (7) 647-652;
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