An overview of therapeutic drug monitoring principles

Charles E. Pippenger, Ph.D
Charles E. Pippenger
Department of Biochemistry, The Cleveland Clinic Foundation
Ph.D
Roles: Head, Section of Applied Clinical Pharmacology
and Ronald P. Lesser, M.D
Ronald P. Lesser
Department of Neurology, The Cleveland Clinic Foundation
M.D
Roles: Director, Adult Seizure Clinic

Cleveland Clinic Journal of Medicine
June 1984,
51
(2)
241-254;

ABSTRACT

Recent technological advances allow determination of anticonvulsant blood levels. Consequently, the principles of pharmacokinetics can be applied in managing patients with seizures. We review these principles as well as those of therapeutic drug monitoring for the control of antiepileptic drug levels.

Index terms

Received November 1983.
Accepted December 1983.

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An overview of therapeutic drug monitoring principles

Charles E. Pippenger

Charles E. Pippenger

and Ronald P. Lesser

Ronald P. Lesser

Cleveland Clinic Journal of Medicine

Jun 1984,

51

(2)

241-254;

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An overview of therapeutic drug monitoring principles

Charles E. Pippenger

Charles E. Pippenger

and Ronald P. Lesser

Ronald P. Lesser

Cleveland Clinic Journal of Medicine

Jun 1984,

51

(2)

241-254;

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