ABSTRACT
Severe digitalis toxicity is associated with a high mortality. We present a case of advanced digoxin toxicity successfully treated with digoxin-specific antibody Fab fragments, and discuss its mechanism of action. A review of the pharmacokinetics of digitalis as well as the mechanisms of cardiotoxicity and its conventional treatment is presented.
- Received July 1986.
- Accepted September 1986.
- Copyright © 1987 The Cleveland Clinic Foundation. All Rights Reserved.