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Review

Fragility fractures in chronic kidney disease: An opinion-based approach

Paul D. Miller, MD
Cleveland Clinic Journal of Medicine December 2009, 76 (12) 715-723; DOI: https://doi.org/10.3949/ccjm.76a.08108
Paul D. Miller
Distinguished Clinical Professor of Medicine, University of Colorado Health Sciences Center, Denver, and Medical Director, Colorado Center for Bone Research, Lakewood, CO
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ABSTRACT

When a patient with chronic kidney disease suffers a fragility fracture, a key question is whether the patient has osteoporosis or, instead, renal osteodystrophy. Bone densitometry does not help in this distinction: biochemical tests, and sometimes also bone biopsy, are needed. However, even if the patient has osteoporosis, we have little evidence to guide our treatment decisions in cases of advanced chronic kidney disease.

Footnotes

  • ↵* The author has disclosed that he has received scientific grants from Amgen, Eli Lilly, Merck & Co, Novartis Pharmaceuticals, Procter & Gamble Pharmaceuticals, Roche Pharmaceuticals, and sanofi-aventis companies; and honoraria for speaking, advising, or consulting from Amgen, Eli Lilly, GlaxoSmithKline, Merck & Co, Novartis Pharmaceuticals, NPS, Procter & Gamble Pharmaceuticals, Roche Pharmaceuticals, and sanofi-aventis companies.

  • Copyright © 2009 The Cleveland Clinic Foundation. All Rights Reserved.
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Cleveland Clinic Journal of Medicine: 76 (12)
Cleveland Clinic Journal of Medicine
Vol. 76, Issue 12
1 Dec 2009
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Fragility fractures in chronic kidney disease: An opinion-based approach
Paul D. Miller
Cleveland Clinic Journal of Medicine Dec 2009, 76 (12) 715-723; DOI: 10.3949/ccjm.76a.08108

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Fragility fractures in chronic kidney disease: An opinion-based approach
Paul D. Miller
Cleveland Clinic Journal of Medicine Dec 2009, 76 (12) 715-723; DOI: 10.3949/ccjm.76a.08108
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