An algorithm for managing warfarin resistance

  • Cleveland Clinic Journal of Medicine
  • December 2009,
  • 76
  • (12)
  • 724-730;
  • DOI: https://doi.org/10.3949/ccjm.76a.09062

ABSTRACT

Some patients need higher-than-expected doses of warfarin (Coumadin) to get their international normalized ratio (INR) into the therapeutic range. The cause of warfarin resistance can be either acquired (eg, poor compliance, drug interactions, dietary interactions) or hereditary, but the genetic mechanisms of warfarin resistance are not well understood. This review offers an algorithm for the evaluation of patients with suspected warfarin resistance.

Loading
  • Print
  • Download PDF
  • Article Alerts
  • Email Article
  • Citation Tools

Jump to section