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Review

Which test for CAD should be used in patients with left bundle branch block?

Bo Xu, MBBS (Hons), Paul Cremer, MD, Wael Jaber, MD, Stuart Moir, MBBS, PhD, Serge C. Harb, MD and L. Leonardo Rodriguez, MD
Cleveland Clinic Journal of Medicine March 2018, 85 (3) 224-230; DOI: https://doi.org/10.3949/ccjm.85a.17051
Bo Xu
Department of Cardiovascular Medicine, Cleveland Clinic
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  • For correspondence: [email protected]
Paul Cremer
Department of Cardiovascular Medicine, Cleveland Clinic
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Wael Jaber
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Stuart Moir
MonashHeart, Monash Medical Centre, Clayton, Victoria, Australia
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Serge C. Harb
Department of Cardiovascular Medicine, Cleveland Clinic
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L. Leonardo Rodriguez
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    Figure 1

    A 12-lead electrocardiogram from a 70-year-old woman with a 12-month history of progressive exertional dyspnea demonstrates sinus rhythm with a ventricular rate of 88 beats per minute and a wide left bundle branch block (QRS duration 150 ms).

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    Figure 2

    Pharmacologic nuclear myocardial perfusion imaging in a 75-year-old woman with atypical symptoms and resting left bundle branch block on electrocardiography. In A, fixed perfusion defects were present at rest and after pharmacologic stress with regadenoson in the septum and apex on single-photon emission computed tomography, mimicking ischemic damage in the left anterior descending artery territory. In B, in comparison, on positron emission tomography, no perfusion abnormalities were seen at rest or with regadenoson.

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    Figure 3

    Proposed diagnostic pathway for patients with suspected obstructive coronary artery disease and resting left bundle branch block.

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Cleveland Clinic Journal of Medicine: 85 (3)
Cleveland Clinic Journal of Medicine
Vol. 85, Issue 3
1 Mar 2018
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Which test for CAD should be used in patients with left bundle branch block?
Bo Xu, Paul Cremer, Wael Jaber, Stuart Moir, Serge C. Harb, L. Leonardo Rodriguez
Cleveland Clinic Journal of Medicine Mar 2018, 85 (3) 224-230; DOI: 10.3949/ccjm.85a.17051

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Which test for CAD should be used in patients with left bundle branch block?
Bo Xu, Paul Cremer, Wael Jaber, Stuart Moir, Serge C. Harb, L. Leonardo Rodriguez
Cleveland Clinic Journal of Medicine Mar 2018, 85 (3) 224-230; DOI: 10.3949/ccjm.85a.17051
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  • Article
    • ABSTRACT
    • LIMITED DATA, GUIDELINES
    • WHAT IS LEFT BUNDLE BRANCH BLOCK?
    • LEFT BUNDLE BRANCH BLOCK AND RISK OF DEATH
    • EXERCISE STRESS ELECTROCARDIOGRAPHY
    • EXERCISE STRESS ECHOCARDIOGRAPHY
    • DOBUTAMINE STRESS ECHOCARDIOGRAPHY
    • NUCLEAR MYOCARDIAL PERFUSION IMAGING
    • CT ANGIOGRAPHY
    • CURRENT GUIDELINES
    • THE POSSIBLE HARMS OF TESTING
    • CLINICAL BOTTOM LINE
    • REFERENCES
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  • Info & Metrics
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