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1-Minute Consult

When can I stop dual antiplatelet therapy in patients with drug-eluting stents?

Juan Simon Rico-Mesa, MD, Carlos Uribe, MD, FACC, FSCAI, Megha Prasad, MD and Sushil Allen Luis, MBBS, FRACP
Cleveland Clinic Journal of Medicine January 2019, 86 (1) 13-16; DOI: https://doi.org/10.3949/ccjm.86a.17033
Juan Simon Rico-Mesa
Department of Medicine, University of Texas Health, San Antonio, TX
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  • For correspondence: [email protected]
Carlos Uribe
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Megha Prasad
Division of Cardiology, Columbia University Medical Center, New York, NY
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Sushil Allen Luis
Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN
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    TABLE 1

    Risk factors for ischemia, stent thrombosis, and bleeding

    IschemiaaStent thrombosisaBleedingb
    Advanced age
    Acute coronary syndrome at presentation
    Previous myocardial infarction
    Extensive coronary artery disease
    Diabetes mellitus
    Chronic kidney disease
    Acute coronary syndrome at presentation
    Diabetes mellitus
    Left ventricular ejection fraction < 40%
    First-generation drug-eluting stent
    Stent undersizing
    Stent underdeployment
    Small stent diameter
    Greater stent length
    Bifurcation stents
    In-stent restenosis
    History of bleeding
    Diabetes mellitus
    Female
    Advanced age
    Low body weight
    Chronic kidney disease
    Anticoagulation
    Chronic nonsteroidal anti-inflammatory drug or steroid therapy
    Anemia
    • ↵a These factors favor consideration of a longer duration of dual antiplatelet therapy.

    • ↵b These factors favor consideration of a shorter duration of dual antiplatelet therapy.

    • Reprinted with permission. Circulation 2016; 134(10):e123–e155. Copyright 2016 American Heart Association, Inc.

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Cleveland Clinic Journal of Medicine: 86 (1)
Cleveland Clinic Journal of Medicine
Vol. 86, Issue 1
1 Jan 2019
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When can I stop dual antiplatelet therapy in patients with drug-eluting stents?
Juan Simon Rico-Mesa, Carlos Uribe, Megha Prasad, Sushil Allen Luis
Cleveland Clinic Journal of Medicine Jan 2019, 86 (1) 13-16; DOI: 10.3949/ccjm.86a.17033

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When can I stop dual antiplatelet therapy in patients with drug-eluting stents?
Juan Simon Rico-Mesa, Carlos Uribe, Megha Prasad, Sushil Allen Luis
Cleveland Clinic Journal of Medicine Jan 2019, 86 (1) 13-16; DOI: 10.3949/ccjm.86a.17033
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  • Article
    • STABLE ISCHEMIC HEART DISEASE VS ACUTE CORONARY SYNDROME
    • BENEFITS OF DAPT
    • THERAPY BEYOND 12 MONTHS
    • EVIDENCE FOR SHORTER DURATION
    • CURRENT GUIDELINES
    • TOOLS TO HELP DECISION-MAKING
    • IF BLEEDING RISK IS HIGH
    • FACING SURGERY
    • CURRENT RESEARCH
    • WHEN STOPPING MAY BE REASONABLE
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