Drug Therapy

  • Is it safe to start steroids at home for a COPD exacerbation after virtual assessment in the COVID-19 era?
    Achintya D. Singh, MBBS, MD, Agrima Mian, MD and James K. Stoller, MD, MS
    Cleveland Clinic Journal of Medicine April 2021, 88 (4) 213-215; DOI: https://doi.org/10.3949/ccjm.88a.20194

    Yes. Corticosteroids are beneficial, and virtual visits are appropriate, especially in this pandemic.

  • Our evolving understanding of primary aldosteronism
    Ali Mehdi, MD, MEd, FACP, Pratibha Rao, MD, MPH and George Thomas, MD
    Cleveland Clinic Journal of Medicine April 2021, 88 (4) 221-227; DOI: https://doi.org/10.3949/ccjm.88a.20166

    Current screening and confirmatory testing lack sensitivity and carry a poor negative predictive value.

  • A cutaneous clue to HIV infection
    Stephen Chan, MD and Paul Aronowitz, MD
    Cleveland Clinic Journal of Medicine March 2021, 88 (3) 145-146; DOI: https://doi.org/10.3949/ccjm.88a.20042

    A retired trucker presented with fever, cough, dyspnea, and a rash on his forehead.

  • Male and female pattern hair loss: Treatable and worth treating
    Nina L. Tamashunas, BS and Wilma F. Bergfeld, MD, FAAD
    Cleveland Clinic Journal of Medicine March 2021, 88 (3) 173-182; DOI: https://doi.org/10.3949/ccjm.88a.20014

    Early recognition and treatment can help preserve as much hair as possible.

  • Frequently asked questions about managing cancer pain: An update
    CME article
    Renato V. Samala, MD, MHPE, FACP, FAAHPM, Ruth L. Lagman, MD, MPH, MBA, FACP, FAAHPM, Sina Najafi, DO and Flannery Fielding, CNP, MSN
    Cleveland Clinic Journal of Medicine March 2021, 88 (3) 183-191; DOI: https://doi.org/10.3949/ccjm.88a.20107

    Pain management can involve pharmacologic and nonpharmacologic therapies.

  • Oral immunotherapy: The answer to peanut allergy?
    Rachel M. Whitsel, APRN, Jaclyn A. Bjelac, MD, Ahila Subramanian, MD, Alice E. W. Hoyt, MD and Sandra J. Hong, MD
    Cleveland Clinic Journal of Medicine February 2021, 88 (2) 104-109; DOI: https://doi.org/10.3949/ccjm.88a.20130

    Gradually increasing doses of the allergen induces tolerance.

  • Cardiac surveillance for anti-HER2 chemotherapy
    Patrick Collier, MD, PhD, FASE, FESC, FACC, Muzna Hussain, MD, Zoran B. Popovic, MD, PhD and Brian P. Griffin, MD
    Cleveland Clinic Journal of Medicine February 2021, 88 (2) 110-116; DOI: https://doi.org/10.3949/ccjm.88a.19150

    A more focused approach is advocated.

  • Precision treatment for metastatic non–small cell lung cancer: A conceptual overview
    Precision treatment for metastatic non–small cell lung cancer: A conceptual overview
    CME article
    Tristan Lee, MD, Jeffrey M. Clarke, MD, Deepali Jain, MD, Sendhilnathan Ramalingam, MD and Vishal Vashistha, MD
    Cleveland Clinic Journal of Medicine February 2021, 88 (2) 117-127; DOI: https://doi.org/10.3949/ccjm.88a.19148

    Targeted therapy has revolutionized treatment of patients with advanced solid tumors.

  • How should you assess glycemic control if the hemoglobin A1c is inaccurate or uninterpretable?
    Wendy O. Henderson, MD, Mary H. Parker, PharmD, FASHP, FCCP, BCPS, BCCP and Bryan C. Batch, MD, MHS
    Cleveland Clinic Journal of Medicine February 2021, 88 (2) 81-85; DOI: https://doi.org/10.3949/ccjm.88a.19135

    Hemoglobin A1c is the standard but is not perfect. Alternatives are available.

  • A 21-year-old woman with Ehlers-Danlos syndrome and persistent lightheadedness
    Raed Qarajeh, MD, Laith A. Derbas, MD, Mouin Abdallah, MD, MSc and Faraz Kureshi, MD, MSc
    Cleveland Clinic Journal of Medicine February 2021, 88 (2) 93-97; DOI: https://doi.org/10.3949/ccjm.88a.19137

    She has a long history of lightheadedness upon standing, and it is getting worse.

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