Drug Therapy

  • A patient with breast cancer and a rash on her hands and feet
    Jonathan Stewart, BS, Grace U. Salacup, MD and Kevin Bryan Uy Lo, MD
    Cleveland Clinic Journal of Medicine January 2021, 88 (1) 22-23; DOI: https://doi.org/10.3949/ccjm.88a.20020

    She had completed her third cycle of chemotherapy 3 days earlier.

  • Cryptosporidiosis in an immunosuppressed patient with persistent diarrhea
    Firas Bahdi, MD, Shilpa Jain, MD and Suneal Kumar Agarwal, MD, FACG
    Cleveland Clinic Journal of Medicine January 2021, 88 (1) 24-26; DOI: https://doi.org/10.3949/ccjm.88a.20016

    A 29-year-old lung transplant recipient presents with diarrhea lasting 1 month.

  • Prescribing testosterone and DHEA: The role of androgens in women
    CME article
    Taryn Smith, MD, NCMP and Pelin Batur, MD, FACP, NCMP
    Cleveland Clinic Journal of Medicine January 2021, 88 (1) 35-43; DOI: https://doi.org/10.3949/ccjm.88a.20030

    Androgens play an important physiologic role and can promote sexual health.

  • Trials and tribulations of testosterone therapy in women: Importance of adhering to the evidence
    Juliana M. Kling, MD, MPH, NCMP, FACP and Sharon J. Parish, MD
    Cleveland Clinic Journal of Medicine January 2021, 88 (1) 44-46; DOI: https://doi.org/10.3949/ccjm.88a.20195

    Testosterone should not be touted for outcomes that are not supported by data.

  • The role of SGLT-2 inhibitors in managing type 2 diabetes
    Yumiko Tsushima, MD, M. Cecilia Lansang, MD, MPH and Vinni Makin, MBBS, MD, FACE
    Cleveland Clinic Journal of Medicine January 2021, 88 (1) 47-58; DOI: https://doi.org/10.3949/ccjm.88a.20088

    These drugs improve glycemic control and offer cardiovascular and metabolic benefits.

  • SGLT-2 inhibitors: A new era in managing diabetic kidney disease starts now
    Jonathan J. Taliercio, DO, George Thomas, MD, Georges N. Nakhoul, MD, MEd, Tushar J. Vachharajani, MD and Ali Mehdi, MD, MEd
    Cleveland Clinic Journal of Medicine January 2021, 88 (1) 59-63; DOI: https://doi.org/10.3949/ccjm.88a.20190

    Randomized controlled trials of these new agents had positive outcomes.

  • 2020: A year like no other
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine December 2020, 87 (12) 710-711; DOI: https://doi.org/10.3949/ccjm.87b.12020

    Veracity and bias are issues we address on a daily basis.

  • COVID-19 coagulopathy
    Anup Katyal, MD
    Cleveland Clinic Journal of Medicine December 2020, 87 (12) 712; DOI: https://doi.org/10.3949/ccjm.87c.12001

    Skepticism of high-intensity prophylaxis for patients with D-dimer ≥ 3.0 µg/mL.

  • In Reply: COVID-19 coagulopathy
    Simon R. Mucha, MD, Siddharth Dugar, MD, Keith McCrae, MD, Douglas Joseph, DO, John Bartholomew, MD, Gretchen L. Sacha, PharmD, RPh, BCCCP and Michael Militello, PharmD, RPh, BCPS
    Cleveland Clinic Journal of Medicine December 2020, 87 (12) 712; DOI: https://doi.org/10.3949/cjm.87c.12002

    An attempt to balance the potential risks and benefits of intensified prophylaxis.

  • Dexamethasone or hydrocortisone in COVID-19?
    Chia Siang Kow, and Syed Shahzad Hasan,
    Cleveland Clinic Journal of Medicine December 2020, 87 (12) 715; DOI: https://doi.org/10.3949/ccjm.87c.12005

    Dexamethasone should be favored over hydrocortisone.

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