Drug Therapy

  • SARS-CoV-2 and myocardial injury: Few answers, many questions
    SARS-CoV-2 and myocardial injury: Few answers, many questions
    Paul C. Cremer, MD
    Cleveland Clinic Journal of Medicine September 2020, 87 (9) 521-525; DOI: https://doi.org/10.3949/ccjm.87a.ccc001

    What is the mechanism? Is this a distinct population? What are the treatment options?

  • 5-Fluorouracil–induced encephalopathy
    Yudai Yano, MD and Akira Kuriyama, MD, MPH
    Cleveland Clinic Journal of Medicine September 2020, 87 (9) 532-533; DOI: https://doi.org/10.3949/ccjm.87a.19126

    A woman on chemotherapy for rectal cancer presents with mental status changes.

  • Polypoid melanoma mistaken for verruca vulgaris
    Andrea Tan, MD, Daniel Gutierrez, MD, Nooshin K. Brinster, MD and Jennifer A. Stein, MD, PhD
    Cleveland Clinic Journal of Medicine September 2020, 87 (9) 534-536; DOI: https://doi.org/10.3949/ccjm.87a.19079

    Polypoid melanoma is highly aggressive and often misdiagnosed.

  • Polymyalgia rheumatica: An updated review
    Salman Bin Mahmood, MBBS, Elizabeth Nelson, MD, Jessica Padniewski, DO and Rawad Nasr, MD
    Cleveland Clinic Journal of Medicine September 2020, 87 (9) 549-556; DOI: https://doi.org/10.3949/ccjm.87a.20008

    Suspect it in older patients with bilateral shoulder and hip stiffness in the morning.

  • Managing adult asthma: The 2019 GINA guidelines
    Yael Mauer, MD, MPH and Rachel Metzger Taliercio, DO
    Cleveland Clinic Journal of Medicine September 2020, 87 (9) 569-575; DOI: https://doi.org/10.3949/ccjm.87a.19136

    All patients should take inhaled corticosteroids daily or as needed.

  • In Reply: Aspirin for primary prevention
    Aldo L. Schenone, MD and A. Michael Lincoff, MD
    Cleveland Clinic Journal of Medicine August 2020, 87 (8) 458-459; DOI: https://doi.org/10.3949/ccjm.87c.08006
  • Aspirin for primary prevention
    Elise Henning, MD, MEd
    Cleveland Clinic Journal of Medicine August 2020, 87 (8) 458; DOI: https://doi.org/10.3949/ccjm.87c.08005
  • Cytokines and the still-baffling clinical biology of COVID-19
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine July 2020, 87 (7) 381-382; DOI: https://doi.org/10.3949/ccjm.87b.07020

    The primary culprit is not certain. Is it all immune damage, or is the continued persistence of coronavirus playing a role?

  • Cytokine storm and the prospects for immunotherapy with COVID-19
    Leonard H. Calabrese, DO
    Cleveland Clinic Journal of Medicine July 2020, 87 (7) 389-393; DOI: https://doi.org/10.3949/ccjm.87a.ccc008

    Despite gaping holes in our knowledge, treatment is evolving.

  • Does a short QT interval increase the risk of cardiac death in healthy people?
    Ahmed Subahi, MD, Ahmed S. Yassin, MD, Oluwole Adegbala, MD, Mohamed Shokr, MD and Luis Afonso, MD
    Cleveland Clinic Journal of Medicine July 2020, 87 (7) 398-400; DOI: https://doi.org/10.3949/ccjm.87a.19090

    No, but it may warrant further investigation to determine if the patient is at risk.

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