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Cleveland Clinic Journal of Medicine
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Cleveland Clinic Journal of Medicine

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Drug Therapy

  • Resistant hypertension: A stepwise approach
    You have access
    Resistant hypertension: A stepwise approach
    CME article
    Jordana Yahr, DO, George Thomas, MD, Juan Calle, MD and Jonathan J. Taliercio, DO
    Cleveland Clinic Journal of Medicine February 2023, 90 (2) 115-125; DOI: https://doi.org/10.3949/ccjm.90a.22046

    The authors review the definition and prevalence of resistant hypertension and its diagnostic workup and management, including lifestyle modifications, drugs, and experimental therapies.

  • You have access
    Balancing the myths of corticosteroid therapy
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine September 2022, 89 (9) 480-481; DOI: https://doi.org/10.3949/ccjm.89b.09022

    No class of drug has more mythical attributes, interfaces with different medical specialties, or clinical street lore than corticosteroids.

  • You have access
    Steroids in the acutely ill: Evolving recommendations and practice
    Stephen M. Pastores, MD, MACP, FCCP, FCCM
    Cleveland Clinic Journal of Medicine September 2022, 89 (9) 505-511; DOI: https://doi.org/10.3949/ccjm.89gr.22002

    New information has been generated with regard to what causes critical illness-related corticosteroid insufficiency, how to diagnose it, who should receive corticosteroid treatment, and what regimens to use.

  • You have access
    Managing stage 1 hypertension: Consider the risks, stop the progression
    Abel Hooker, MD, Kevin G. Buda, DO and Maarya Pasha, MD
    Cleveland Clinic Journal of Medicine May 2022, 89 (5) 244-248; DOI: https://doi.org/10.3949/ccjm.89a.21101

    Guidelines on managing patients with stage 1 hypertension and a low 10-year risk of atherosclerotic cardiovascular disease.

  • You have access
    Psychogenic nonepileptic seizure: An empathetic, practical approach
    Becky Bikat S. Tilahun, PhD and Jocelyn F. Bautista, MD
    Cleveland Clinic Journal of Medicine May 2022, 89 (5) 252-259; DOI: https://doi.org/10.3949/ccjm.89a.21109

    Barriers to care include clinician misperceptions, lack of acceptance of the diagnosis, poor patient engagement with treatment, and lack of access to care.

  • You have access
    Psychogenic nonepileptic seizure: A neurologist’s perspective
    Elaine Wyllie, MD
    Cleveland Clinic Journal of Medicine May 2022, 89 (5) 260-261; DOI: https://doi.org/10.3949/ccjm.89a.21129

    Confirming the diagnosis is only the start of the journey. The greater challenge and opportunity lie in how physicians present the diagnosis to the patient and family.

  • Esophageal adenocarcinoma: A dire need for early detection and treatment
    You have access
    Esophageal adenocarcinoma: A dire need for early detection and treatment
    CME article
    Abel Joseph, MD, Siva Raja, MD, PhD, Suneel Kamath, MD, Sunguk Jang, MD, Daniela Allende, MD, Mike McNamara, MD, Gregory Videtic, MD, Sudish Murthy, MD and Amit Bhatt, MD
    Cleveland Clinic Journal of Medicine May 2022, 89 (5) 269-279; DOI: https://doi.org/10.3949/ccjm.89a.21053

    A clinical overview focused on screening, multidisciplinary evaluation, and treatment of early esophageal adenocarcinoma.

  • You have access
    Treating anemia: It’s not just the EPO
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine April 2022, 89 (4) 174-175; DOI: https://doi.org/10.3949/ccjm.89b.04022

    Long-term effects of treatment with the new oral inhibitors of prolyl hydroxylase will need to be carefully monitored, as prolyl hydroxylase is a key structural component of diverse proteins.

  • You have access
    Oral hyperpigmentation with weakness and salt-craving
    Joseph Zhou, MD and S. Sethu K. Reddy, MD, MBA, FRCPC, FACP, MACE
    Cleveland Clinic Journal of Medicine April 2022, 89 (4) 180-181; DOI: https://doi.org/10.3949/ccjm.89a.21036

    The patient’s primary care physician had attributed the hyperpigmentation on the lower lip and inner cheek to pen ink.

  • You have access
    Glycemic targets in the ICU: A look back, and ahead
    Keren Zhou, MD
    Cleveland Clinic Journal of Medicine April 2022, 89 (4) 189-190; DOI: https://doi.org/10.3949/ccjm.89a.21127

    Much work is still needed to understand the nuances of glycemic targets in critically ill patients, and to learn how to take advantage of evolving technology to improve glycemic control.

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