Review

Acute kidney injury after hip or knee replacement: Can we lower the risk?

Edward J. Filippone, MD, FASN and Anju Yadav, MD
Cleveland Clinic Journal of Medicine April 2019, 86 (4) 263-276; DOI: https://doi.org/10.3949/ccjm.86a.18044

ABSTRACT

Patients who undergo hip or knee replacement (total joint arthroplasty) face a risk of acute kidney injury that may be higher than previously thought and that increases steeply if they undergo surgical revision to treat prosthetic joint infection. This article assesses the incidence of and risk factors for acute kidney injury after primary total joint arthroplasty or placement of an antibiotic-loaded cement spacer to treat infection, and offers suggestions on how to reduce the risk.

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  1. Edward J. Filippone, MD, FASN⇑
  1. Clinical Associate Professor of Medicine, Department of Medicine, Division of Nephrology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA
  1. ADDRESS:
    Edward J. Filippone, MD, FASN, Department of Medicine, Division of Nephrology, Sidney Kimmel Medical College, Thomas Jefferson University, 2228 South Broad Street, Philadelphia, PA 19145; kidneys{at}comcast.net
  1. Anju Yadav, MD
  1. Assistant Professor, Department of Medicine, Division of Nephrology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA

ABSTRACT

Patients who undergo hip or knee replacement (total joint arthroplasty) face a risk of acute kidney injury that may be higher than previously thought and that increases steeply if they undergo surgical revision to treat prosthetic joint infection. This article assesses the incidence of and risk factors for acute kidney injury after primary total joint arthroplasty or placement of an antibiotic-loaded cement spacer to treat infection, and offers suggestions on how to reduce the risk.

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