Nephrology
- High-output heart failure from arteriovenous dialysis access: A structured approach to diagnosis and management
Arteriovenous high-output heart failure is likely underdiagnosed because many clinicians are uncertain about when and how to evaluate for it.
IgA nephropathy: Update on pathogenesis and treatmentRenin-angiotensin-aldosterone system inhibitors or corticosteroids remain the cornerstone of therapy, but new agents targeting the different “hits” in the pathogenesis of IgA nephropathy are being introduced.
- Do I need to treat supine hypertension in my hospitalized patient?
Inpatients with an elevated supine blood pressure should be evaluated for orthostatic changes before treatment is considered.
- Common electrolyte imbalance, uncommon cause
A 47-year-old woman presented with 10 days of weakness, wide purple striae on the abdomen, and hyperpigmentation on the knuckles.
Should my patients with hypertension be referred for renal denervation?Renal denervation may be appropriate as an alternative or adjunct to pharmacotherapy in certain patients. Shared decision-making is crucial before proceeding.
- SGLT-2 inhibitors: Diabetes and CKD and CHF (and gout?), oh my!
What mechanisms might account for the diverse beneficial effects of the SGLT-2 inhibitors observed across various diseases?
SGLT-2 inhibitors in heart failure and chronic kidney disease: A review for internistsThis review summarizes recent data and guidelines regarding SGLT-2 inhibitors in heart failure and chronic kidney disease and provides practical guidance for their use.
- A hidden cause of hypokalemia
A 21-year-old man presented with increasing fatigue and psychosis symptoms. Laboratory testing results were consistent with a metabolic disorder.