Infectious Diseases

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    Fatigue and dyspnea in a 71-year-old man with a pulmonary nodule

    Suprita Degala, MBBS, Hamritha Tamilvel, MBBS, Jana Berro, MD, Atul C. Mehta, MD and Grant Senyei, MD
    • Cleveland Clinic Journal of Medicine September 2026, 93 (9) 533-539;
    • DOI: https://doi.org/10.3949/ccjm.93a.26011

    • Chest computed tomography showed a solid pulmonary nodule in the right lower lobe that was absent on imaging 1 year earlier.

  • A painful ulcerative lesion on the lip

    Reuben J. Arasaratnam, MD, MPH, Lenka Stankova, MD, Joseph L. Milburn, MD, Bradford T. Barker, MD, Megan B. Wachsmann, MD and Donald F. Storey, MD
    • Cleveland Clinic Journal of Medicine September 2026, 93 (9) 512-514;
    • DOI: https://doi.org/10.3949/ccjm.93a.26033

    • In addition to progressive ulceration of the right lower lip, the patient had a 1-year history of reduced appetite and a 20-pound weight loss.

  • Lemierre syndrome (septic thrombophlebitis of the internal jugular vein)

    Daichi Yomogida, MD, Shinjiro Horikawa, MD, PhD and Yoshinao Koshida, MD, PhD
    • Cleveland Clinic Journal of Medicine September 2026, 93 (9) 510-511;
    • DOI: https://doi.org/10.3949/ccjm.93a.26012

    • The patient presented with fever and left chest pain more than 2 weeks after experiencing common cold symptoms.

  • Mucocutaneous rash after respiratory infection

    Mandlin Abdulaziz Almousa, DMD, Narath Carlile, MD, MPH and Nathaniel Treister, DMD, DMSc
    • Cleveland Clinic Journal of Medicine August 2026, 93 (8) 457-458;
    • DOI: https://doi.org/10.3949/ccjm.93a.26001

    • The patient presented with conjunctivitis, skin rash, and oral and genital mucosal lesions 2 weeks after being ill with a fever, productive cough, and myalgia.

  • Postinfectious immunologic syndromes

    Brian F. Mandell, MD, PhD
    • Cleveland Clinic Journal of Medicine August 2026, 93 (8) 447-448;
    • DOI: https://doi.org/10.3949/ccjm.93b.08026

    • Activation of the immune system can be associated with many off-target manifestations.

  • Pseudocellulitis, a vague term for a specific diagnostic challenge

    Brian F. Mandell, MD, PhD
    • Cleveland Clinic Journal of Medicine June 2026, 93 (6) 313-314;
    • DOI: https://doi.org/10.3949/ccjm.93b.06026

    • There are infectious, vascular, and inflammatory conditions that can mimic cellulitis sufficiently to prompt admission and initial treatment with intravenous antibiotics.

  • Disseminated coccidioidomycosis masquerading as bacterial cellulitis

    Santana Maria Bachaalany, DO, Nelson Nicolasora, MD, Lindsay Ackerman, MD, Ghassan Ibrahim, MD and Trent Smith, MD
    • Cleveland Clinic Journal of Medicine June 2026, 93 (6) 321-323;
    • DOI: https://doi.org/10.3949/ccjm.93a.25096

    • The patient exhibited signs of sepsis along with progressive left breast erythema, induration, and pain.

  • Iris roseola: A diagnostic clue in neurosyphilis

    Victor Alegre-Ituarte, MD, PhD and Elena Franz-Lacomba, MD
    • Cleveland Clinic Journal of Medicine May 2026, 93 (5) 259-260;
    • DOI: https://doi.org/10.3949/ccjm.93a.25047

    • The patient had a 3-week history of decreased vision in the left eye, with a best-corrected visual acuity of 20/100.

  • Varicella-zoster virus transmission from herpes zoster exposure

    Ayano Takeiri, MD, Kentaro Ishikura, MD and Yoshitaka Tomoda, MD, PhD
    • Cleveland Clinic Journal of Medicine May 2026, 93 (5) 261-262;
    • DOI: https://doi.org/10.3949/ccjm.93a.25068

    • Two weeks before the patient developed fever and a rash, his mother had developed herpes zoster on her torso.

  • Vaccine hesitancy: Where are we heading?

    Sherif Beniameen Mossad, MD
    • Cleveland Clinic Journal of Medicine January 2026, 93 (1) 21-26;
    • DOI: https://doi.org/10.3949/ccjm.93a.25104

    • Vaccination recently was hailed as one of the top 10 public health achievements of the 20th century; now, the World Health Organization lists vaccine hesitancy among the top 10 threats to global health.

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