Infectious Diseases

  • Vaccine hesitancy: Where are we heading?
    Sherif Beniameen Mossad, MD
    Cleveland Clinic Journal of Medicine January 2026, 93 (1) 21-26; DOI: https://doi.org/10.3949/ccjm.93a.25104

    Vaccination recently was hailed as one of the top 10 public health achievements of the 20th century; now, the World Health Organization lists vaccine hesitancy among the top 10 threats to global health.

  • Corticosteroids in severe community-acquired pneumonia
    Enmanuel A. Leiva-Murillo, MD and Rosanel Amaro-Rodríguez, MD, PhD
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 723-724; DOI: https://doi.org/10.3949/ccjm.92c.12005
  • In Reply: Corticosteroids in severe community-acquired pneumonia
    Alejandro Chapa-Rodriguez, MD, Tark Abou-Elmagd, MD, Cody O’Rear, DO and Shraddha Narechania, MD
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 724; DOI: https://doi.org/10.3949/ccjm.92c.12006
  • Skin manifestations of mpox
    James Kim, MD, Matt Biondi, MD and Helen Bartels, MB, BChir
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 736-737; DOI: https://doi.org/10.3949/ccjm.92a.25022

    The patient presented with a tender, ulcerated perianal lesion and scattered papules on the trunk and extremities.

  • Multiple scabietic nodules on the scrotum in a patient living with HIV infection
    Hidenori Nakagawa, MD, Akiko Imanishi, MD, Tomohiro Asaoka, MD and Michinori Shirano, MD, PhD
    Cleveland Clinic Journal of Medicine November 2025, 92 (11) 654-655; DOI: https://doi.org/10.3949/ccjm.92a.24121

    A 21-year-old man presented with pruritic erythematous papules and nodules on the scrotum and linear keratotic burrows on the right wrist.

  • Do patients with severe community-acquired bacterial pneumonia benefit from systemic corticosteroids?
    Alejandro Chapa-Rodriguez, MD, Tark Abou-Elmagd, MD, MSc, MBBCh, Cody O’Rear, DO and Shraddha Narechania, MD
    Cleveland Clinic Journal of Medicine October 2025, 92 (10) 600-604; DOI: https://doi.org/10.3949/ccjm.92a.25023

    Recent evidence has swung the pendulum back in favor of using corticosteroids in patients with severe community-acquired pneumonia.

  • Nearly a century of using glucocorticoids in patients with active infection
    Adam J. Brown, MD
    Cleveland Clinic Journal of Medicine October 2025, 92 (10) 605-608; DOI: https://doi.org/10.3949/ccjm.92a.25074

    Why would we consider dampening the immune response with glucocorticoids when a patient has an active infection?

  • Cerebrovascular complications in infective endocarditis: Challenges and considerations in management
    Cerebrovascular complications in infective endocarditis: Challenges and considerations in management
    Vikyath Satish, MD, Maisha Maliha, MD, Abhyuday Chauhan, MD, Nieves del Mar Morales-Gomez, MD, Safwan Gaznabi, MD, Daniel Lorenzatti, MD, Justin Johannesen, MD, Carlos A. Gongora, MD, Annalisa Filtz, MD, Mario J. Garcia, MD, Leandro Slipczuk, MD, PhD and Aldo L. Schenone, MD
    Cleveland Clinic Journal of Medicine August 2025, 92 (8) 491-501; DOI: https://doi.org/10.3949/ccjm.92a.24087

    Although the cerebrovascular complications of infective endocarditis such as ischemic strokes and intracranial hemorrhages are common and serious, data remain scarce regarding how best to prevent, predict, and manage them.

  • Odontogenic cutaneous fistula
    Sagar Khanna, BDS, DDS
    Cleveland Clinic Journal of Medicine July 2025, 92 (7) 399-400; DOI: https://doi.org/10.3949/ccjm.92a.24096

    A 55-year-old woman with a history of systemic lupus erythematosus and secondary Sjögren syndrome presented with a 2-year history of facial swelling and intermittent drainage from a skin lesion on her left jaw.

  • Fecal microbiota transplantation: Current evidence and future directions
    Fecal microbiota transplantation: Current evidence and future directions
    Michael Cymbal, DO, Arjun Chatterjee, MD and Brian Baggott, MD
    Cleveland Clinic Journal of Medicine July 2025, 92 (7) 421-428; DOI: https://doi.org/10.3949/ccjm.92a.24107

    Fecal microbiota transplantation is recognized for effectively treating recurrent Clostridioides difficile infection, prompting further investigation into its other possible clinical applications.

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