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Review

Myocardial infarction with nonobstructive coronary arteries: Current management strategies

Kevin G. Buda, DO, Sanjoyita Mallick, DO and Louis P. Kohl, MD
Cleveland Clinic Journal of Medicine December 2024, 91 (12) 743-753; DOI: https://doi.org/10.3949/ccjm.91a.19127
Kevin G. Buda
Cardiology Division, Department of Internal Medicine, Hennepin Healthcare, Minneapolis, MN; Minneapolis Heart Institute and Abbott Northwestern Hospital, Minneapolis, MN
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Sanjoyita Mallick
Department of Medicine, Hennepin Healthcare, Minneapolis, MN
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  • For correspondence: [email protected]
Louis P. Kohl
Cardiology Division, Department of Internal Medicine, Hennepin Healthcare, Minneapolis, MN
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  • Release date: December 1, 2024
  • Expiration date: November 30, 2025
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ABSTRACT

From 6% to 8% of patients who present with myocardial infarction have no evidence of obstructive coronary artery disease on angiography. This subgroup tends to be younger, and more of them are women. This review highlights a proposed algorithm to identify the underlying cause of myocardial infarction with nonobstructive coronary arteries (MINOCA). We emphasize the need for a collaborative approach in diagnosing and managing MINOCA to improve patient outcomes, advocating for a standardized diagnostic pathway that incorporates cardiac magnetic resonance imaging and comprehensive clinical evaluation to tailor treatments effectively.

  • Copyright © 2024 The Cleveland Clinic Foundation. All Rights Reserved.
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  1. Kevin G. Buda, DO
  1. Cardiology Division, Department of Internal Medicine, Hennepin Healthcare, Minneapolis, MN; Minneapolis Heart Institute and Abbott Northwestern Hospital, Minneapolis, MN
  1. Sanjoyita Mallick, DO⇑
  1. Department of Medicine, Hennepin Healthcare, Minneapolis, MN
  1. Address:
    Sanjoyita Mallick, DO, Department of Medicine, Hennepin Healthcare, 701 Park Avenue, Minneapolis, MN 55415-1829; Sanjoyita.mallick{at}hcmed.org
  1. Louis P. Kohl, MD
  1. Cardiology Division, Department of Internal Medicine, Hennepin Healthcare, Minneapolis, MN

ABSTRACT

From 6% to 8% of patients who present with myocardial infarction have no evidence of obstructive coronary artery disease on angiography. This subgroup tends to be younger, and more of them are women. This review highlights a proposed algorithm to identify the underlying cause of myocardial infarction with nonobstructive coronary arteries (MINOCA). We emphasize the need for a collaborative approach in diagnosing and managing MINOCA to improve patient outcomes, advocating for a standardized diagnostic pathway that incorporates cardiac magnetic resonance imaging and comprehensive clinical evaluation to tailor treatments effectively.

  • Copyright © 2024 The Cleveland Clinic Foundation. All Rights Reserved.
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Cleveland Clinic Journal of Medicine: 91 (12)
Cleveland Clinic Journal of Medicine
Vol. 91, Issue 12
1 Dec 2024
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Myocardial infarction with nonobstructive coronary arteries: Current management strategies
Kevin G. Buda, Sanjoyita Mallick, Louis P. Kohl
Cleveland Clinic Journal of Medicine Dec 2024, 91 (12) 743-753; DOI: 10.3949/ccjm.91a.19127

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Myocardial infarction with nonobstructive coronary arteries: Current management strategies
Kevin G. Buda, Sanjoyita Mallick, Louis P. Kohl
Cleveland Clinic Journal of Medicine Dec 2024, 91 (12) 743-753; DOI: 10.3949/ccjm.91a.19127
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Jump to section

  • Article
    • ABSTRACT
    • MYOCARDIAL INFARCTIONS DEFINED AND CLASSIFIED
    • MINOCA AS A CLINICAL CONDITION
    • NUTS AND BOLTS OF THE AHA STATEMENT
    • A TRAFFIC-LIGHT ALGORITHM FOR DIAGNOSING MINOCA
    • CASE CONTINUED: SEPTAL BRANCH OCCLUSION
    • OUTCOMES BY SUBTYPE UNCERTAIN
    • MAJOR CAUSES OF MINOCA
    • CLINICAL WORKUP OF MINOCA: WHAT’S NEW?
    • TREATMENT
    • DISCLOSURES
    • REFERENCES
  • Figures & Data
  • Info & Metrics
  • PDF

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