Is there a role for chronic suppressive therapy in herpes simplex virus infection?

Article Figures & Data

TABLE 1

Episodic treatment regimens for recurrent herpes simplex virus infection

Medication	Dose and duration
Acyclovir	800 mg 3 times daily for 2 days 800 mg twice daily for 5 days
Famciclovir	1,000 mg twice daily for 1 day 500 mg once, then 250 mg twice daily for 2 days 125 mg twice daily for 5 days
Valacyclovir	500 mg twice daily for 3 days 1,000 mg once daily for 5 days

TABLE 2

Chronic suppressive regimens in patients without and with HIV infection

Medication	Patients without HIV	Patients with HIV or immunosuppressive condition
Acyclovir	400 mg twice daily	400 mg to 800 mg 2–3 times a day
Valacyclovir	500 mg to 1,000 mg once daily	500 mg twice daily
Famciclovir	250 mg twice daily	500 mg twice daily