More articles from Symptoms to Diagnosis

  • Acute vertigo in a 67-year-old woman: Peripheral or central?

    David Kweku Aseda Donkor, MD, Kapil Nayar, MD and Jerma Adams, MD
    • Cleveland Clinic Journal of Medicine October 2026, 93 (10) 592-596;
    • DOI: https://doi.org/10.3949/ccjm.93a.26035

    • The patient presented with dizziness that started earlier that morning when she rose from bed, persisted after she returned to bed, and worsened with head movement.

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    Fatigue and dyspnea in a 71-year-old man with a pulmonary nodule

    Suprita Degala, MBBS, Hamritha Tamilvel, MBBS, Jana Berro, MD, Atul C. Mehta, MD and Grant Senyei, MD
    • Cleveland Clinic Journal of Medicine September 2026, 93 (9) 533-539;
    • DOI: https://doi.org/10.3949/ccjm.93a.26011

    • Chest computed tomography showed a solid pulmonary nodule in the right lower lobe that was absent on imaging 1 year earlier.

  • A 70-year-old man with lower-extremity weakness and falls

    Calen Frolkis, MD, Ari Wachsman, MD, Angela Liu, MD, PhD and Ayoub Harb, DO
    • Cleveland Clinic Journal of Medicine July 2026, 93 (7) 409-417;
    • DOI: https://doi.org/10.3949/ccjm.93a.25061

    • After multiple imaging studies were performed, a thorough examination at the bedside appropriately broadened the differential diagnosis.

  • Hematochezia in a patient with end-stage renal disease

    Brennan Gioe, MD, Conrad Fernandes, MD, E. Celia Marginean, MD and Stalin Subramanian, MD
    • Cleveland Clinic Journal of Medicine June 2026, 93 (6) 333-338;
    • DOI: https://doi.org/10.3949/ccjm.93a.25097

    • The patient developed gastrointestinal bleeding after being started on intravenous heparin following thrombectomy and angioplasty for acute limb ischemia.

  • Unexplained liver injury: Searching for the cause

    Mohamed Eldib, MD, William D. Carey, MD and Blazenka Skugor, MD
    • Cleveland Clinic Journal of Medicine May 2026, 93 (5) 267-272;
    • DOI: https://doi.org/10.3949/ccjm.93a.25099

    • The patient presented with persistent low back pain, nausea, poor appetite, and an unintentional weight loss of more than 30 lb over the previous 6 weeks.

  • A 20-year-old woman with a 9-year history of shortness of breath

    Jack Johnson, OMS-1, Karishma Lukose, MS4 and Mary C. Labanowski, MD
    • Cleveland Clinic Journal of Medicine April 2026, 93 (4) 211-217;
    • DOI: https://doi.org/10.3949/ccjm.93a.25073

    • The patient had been given diagnoses of bronchitis, asthma, and COVID-19, and was previously treated with antibiotics as well as inhaled bronchodilators and steroids.

  • A 24-year-old man with severe hemolytic anemia and variable Coombs test results

    Sindu Iska, MD, María Herrán, MD, You Li, MD, Maria Teresa Bejarano, MD, Chakra P. Chaulagain, MD and Chieh-Lin Fu, MD
    • Cleveland Clinic Journal of Medicine March 2026, 93 (3) 159-168;
    • DOI: https://doi.org/10.3949/ccjm.93a.25079

    • The patient was admitted to the hospital because of dark urine, jaundice, fatigue, and confusion.

  • Rapidly progressive kidney failure in an 82-year-old man with respiratory symptoms

    CME Image
    Bernardo Henrique Mendes Correa, MD, Ali Mushtaq, MD, Ali Awada, Faiz Anwer, MD and Anam Ashfaque, MD
    • Cleveland Clinic Journal of Medicine February 2026, 93 (2) 99-105;
    • DOI: https://doi.org/10.3949/ccjm.93a.25037

    • The patient presented to the emergency department due to worsening dry cough, lower-extremity edema, and fatigue, all of which had begun about 2 weeks earlier.

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    Right ventricular failure in a young man

    Keerthana Sankar, MD and Yuri Matusov, MD
    • Cleveland Clinic Journal of Medicine February 2026, 93 (2) 106-112;
    • DOI: https://doi.org/10.3949/ccjm.93a.25048

    • The patient initially experienced dyspnea only on exertion, but over the 2 months before presentation it had progressed to shortness of breath at rest.

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    A young woman with Kallmann syndrome and acute neurologic symptoms

    Jumaina F. Ali, MBChB, Adhithya Sankar, MBChB, PhD, Mohammed S. O. Ahmed, MBBS, MSc, Mark Woodward, BSc (Hons), MBChB and Akheel A. Syed, MBBS, PhD
    • Cleveland Clinic Journal of Medicine January 2026, 93 (1) 29-34;
    • DOI: https://doi.org/10.3949/ccjm.93a.25010

    • Diagnoses considered on initial presentation included conditions that present with stroke-like symptoms such as seizure, hemiplegic migraine, transient ischemic attack, and brain tumor.

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