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Cleveland Clinic Journal of Medicine
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Cleveland Clinic Journal of Medicine

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Most read article(s)

  • You have access
    Should I consider metformin therapy for weight loss in patients with obesity but without diabetes?
    Paloma Rodriguez, MD, Kevin M. Pantalone, DO, ECNU, FACE, Marcio L. Griebeler, MD and Bartolome Burguera, MD, PhD
    Cleveland Clinic Journal of Medicine September 2023, 90 (9) 545-548; DOI: https://doi.org/10.3949/ccjm.90a.22096

    The authors appraise the evidence to date for weight loss with metformin in this patient population.

  • You have access
    Prolonged venous filling time and dependent rubor in a patient with peripheral artery disease
    Scott L. Hagan, MD and Jeffrey W. Redinger, MD
    Cleveland Clinic Journal of Medicine April 2025, 92 (4) 205-206; DOI: https://doi.org/10.3949/ccjm.92a.24056

    Physical examination in a man who presented with foot pain revealed absent bilateral posterior tibial and dorsalis pedis pulses and dusky erythema of both feet.

  • You have access
    2024 ACC/AHA guideline on perioperative cardiovascular management before noncardiac surgery: What’s new?
    CME article
    Steven L. Cohn, MD
    Cleveland Clinic Journal of Medicine April 2025, 92 (4) 213-219; DOI: https://doi.org/10.3949/ccjm.92a.24125

    The author highlights key changes and recommendations of the new guideline, how they differ from previous and other society guidelines, and ongoing challenges and unresolved issues in perioperative care.

  • You have access
    Evaluation of nail lines: Color and shape hold clues
    Shari R. Lipner, MD, PhD and Richard K. Scher, MD, FACP
    Cleveland Clinic Journal of Medicine May 2016, 83 (5) 385-391; DOI: https://doi.org/10.3949/ccjm.83a.14187

    Inspection of the fingernails and toenails should be part of a complete physical examination.

  • You have access
    Cardiovascular disease in people living with HIV: Risk assessment and management
    Elizabeth Ghandakly, MD, JD, Rohit Moudgil, MD, PhD and Katherine Holman, MD
    Cleveland Clinic Journal of Medicine March 2025, 92 (3) 159-167; DOI: https://doi.org/10.3949/ccjm.92a.24055

    Because people living with HIV develop coronary artery disease much earlier than the general population, careful attention must be given to assessment and management of their cardiovascular risk.

  • You have access
    Heart to heart: Progress in cardiovascular disease prevention for people living with HIV
    James Hekman, MD and Henry H. Ng, MD, MPH
    Cleveland Clinic Journal of Medicine March 2025, 92 (3) 168-170; DOI: https://doi.org/10.3949/ccjm.92a.24126

    The already higher cardiovascular risk in people living with HIV is exacerbated by social determinants of health such as socioeconomic status, access to healthcare, and systemic discrimination. Interventions that address this risk must be based in medical science and equity.

  • You have access
    Paroxysmal finger hematoma
    Daan J.L. van Twist, MD, PhD, Wim Hermans and Guy J.M. Mostard, MD
    Cleveland Clinic Journal of Medicine April 2020, 87 (4) 194; DOI: https://doi.org/10.3949/ccjm.87a.19122

    This benign, self-limiting condition predominantly affects middle-aged women.

  • You have access
    Shortness of breath in a 52-year-old man with HIV and severe mitral regurgitation
    Felix Wangmang, MD, PharmD, Achilles Aiken, MD and Kuang-Yuh Chyu, MD, PhD
    Cleveland Clinic Journal of Medicine January 2025, 92 (1) 23-30; DOI: https://doi.org/10.3949/ccjm.92a.24060

    The patient presented with 3 weeks of acute on chronic dyspnea on exertion with progression to dyspnea at rest and associated orthopnea.

  • You have access
    Quetiapine for primary insomnia: Consider the risks
    Vania Modesto-Lowe, MD, MPH, Agata K. Harabasz, MD and Sophia A. Walker, MD
    Cleveland Clinic Journal of Medicine May 2021, 88 (5) 286-294; DOI: https://doi.org/10.3949/ccjm.88a.20031

    Its cardiometabolic effects and potential for abuse warrant caution in off-label use.

  • You have access
    Should glucagon-like peptide 1 receptor agonists be withheld during the preoperative period?
    Sneha Mishra, MBBS, Patress A. Persons, MD and Sophie Bersoux, MD, MPH
    Cleveland Clinic Journal of Medicine April 2025, 92 (4) 209-211; DOI: https://doi.org/10.3949/ccjm.92a.24110

    Clinical judgment should guide this decision, taking into account patient symptoms and the presence of factors that may delay gastric emptying and increase risk for aspiration.

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