Most read article(s)

  • Vitamin D supplementation: Pearls for practicing clinicians
    Susan E. Williams, MS, RD, MD, CCD, FACE, FAND
    Cleveland Clinic Journal of Medicine March 2022, 89 (3) 154-160; DOI: https://doi.org/10.3949/ccjm.89a.21021

    A review of how to assess and counsel patients on the use of vitamin D, with patient scenarios clinicians are likely to encounter, and an overview of current recommendations for vitamin D supplementation.

  • Most elderly patients with subclinical hypothyroidism do not need to be treated
    Most elderly patients with subclinical hypothyroidism do not need to be treated
    Risheng Xu, DO, Nicola Abate, MD, Nalini Ram, MD and Kristina Little, MD
    Cleveland Clinic Journal of Medicine April 2025, 92 (4) 221-231; DOI: https://doi.org/10.3949/ccjm.92a.24098

    Age-adjusted thyrotropin reference ranges, consideration of individual circumstances, and a wait-and-see approach for mild subclinical hypothyroidism might be more suitable than a universal treatment strategy.

  • Psychedelics in the medical toolbox?
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine April 2025, 92 (4) 200-201; DOI: https://doi.org/10.3949/ccjm.92b.04025

    Given the historical association of psychedelics as “recreational” mind-altering compounds within countercultures of the 1960s and 1970s, their current introduction into several aspects of medical practice is a surprise to many.

  • Meeting the challenge of vaccine hesitancy CME article
    Oluwatosin Goje, MD, MSCR, FACOG and Aanchal Kapoor, MD, MEd
    Cleveland Clinic Journal of Medicine September 2024, 91 (9 suppl 1) S50-S56; DOI: https://doi.org/10.3949/ccjm.91.s1.08
  • Nociplastic pain: A practical guide to chronic pain management in the primary care setting
    CME article
    Rupak Thapa, MD and Dennis Ang, MD
    Cleveland Clinic Journal of Medicine April 2025, 92 (4) 236-247; DOI: https://doi.org/10.3949/ccjm.92a.24101

    Nociplastic pain is characterized by amplification of pain transmission and pain perception and does not involve visible tissue injury or damage, which makes it difficult to understand and manage.

  • Subclinical hypothyroidism: What’s in a name?
    Jennifer S. Mammen, MD, PhD
    Cleveland Clinic Journal of Medicine April 2025, 92 (4) 233-235; DOI: https://doi.org/10.3949/ccjm.92a.25028

    Clinicians should remain thoughtful about the variability in aging biology and not be blinded by a name.

  • Psychedelics, spirituality, and existential distress in patients at the end of life
    Nicole Cornish, PharmD, Tara Coles, MD, M. Jennifer Cheng, MD, Claudia Ruiz Sotomayor, MD, DBe, Aaron Wolfgang, MD and Christopher Spevak, MD, MPH, JD
    Cleveland Clinic Journal of Medicine April 2025, 92 (4) 248-254; DOI: https://doi.org/10.3949/ccjm.92a.24100

    The authors explore the role of psychedelics in addressing patients’ spiritual and existential suffering at the end of life from a medical, ethical, and legal perspective.

  • Central sensitization, chronic pain, and other symptoms: Better understanding, better management
    Mary M. Volcheck, MSN, RN, Stephanie M. Graham, RN, Kevin C. Fleming, MD, Arya B. Mohabbat, MD and Connie A. Luedtke, RN, PMGT-BC
    Cleveland Clinic Journal of Medicine April 2023, 90 (4) 245-254; DOI: https://doi.org/10.3949/ccjm.90a.22019

    Clinicians have a pivotal role by providing patient education, which can affect perception, management, functional status, and quality of life.

  • Cannabis for peripheral neuropathy: The good, the bad, and the unknown
    Vania Modesto-Lowe, MD, MPH, Rachel Bojka, MS, PA-C and Camille Alvarado, DO, MPH
    Cleveland Clinic Journal of Medicine December 2018, 85 (12) 943-949; DOI: https://doi.org/10.3949/ccjm.85a.17115

    Even where it is legal, doctors should recommend it only after careful consideration.

  • Three neglected numbers in the CBC: The RDW, MPV, and NRBC count
    Jori E. May, MD, Marisa B. Marques, MD, Vishnu V.B. Reddy, MD and Radhika Gangaraju, MD
    Cleveland Clinic Journal of Medicine March 2019, 86 (3) 167-172; DOI: https://doi.org/10.3949/ccjm.86a.18072

    These values have diagnostic utility and potential prognostic significance.

Pages