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Review

Pharmacotherapy of multiple sclerosis: current status

Richard A. Rudick, MD, Donald E. Goodkin, MD and Richard M. Ransohoff, MD
Cleveland Clinic Journal of Medicine May 1992, 59 (3) 267-277;
Richard A. Rudick
Mellen Center for Multiple Sclerosis Treatment and Research, Department of Neurology, The Cleveland Clinic Foundation.
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Donald E. Goodkin
Mellen Center for Multiple Sclerosis Treatment and Research, Department of Neurology, The Cleveland Clinic Foundation.
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Richard M. Ransohoff
Mellen Center for Multiple Sclerosis Treatment and Research, Department of Neurology, The Cleveland Clinic Foundation.
Department of Molecular Biology, The Cleveland Clinic Foundation.
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ABSTRACT

Pharmacotherapy plays an important part in the overall management of patients with multiple sclerosis. Most therapies directed at altering the natural history of the underlying disease process are only partially effective or are controversial or experimental. However, many effective symptomatic therapies are available to the clinician. The action and uses of corticosteroids in multiple sclerosis are discussed, and approaches to the treatment of spasticity, paroxysmal disorders, bladder dysfunction, cerebellar ataxia, neurobehavioral manifestations, fatigue, and acute and chronic pain in patients with multiple sclerosis are examined.

INDEX TERMS
  • Multiple Sclerosis
  • Azathioprine
  • Polymers
  • Cyclophosphamide
  • Cyclosporins
  • Interferons
  • Plasmapheresis
  • Lymphatic Irradiation
  • Copyright © 1992 The Cleveland Clinic Foundation. All Rights Reserved.
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Cleveland Clinic Journal of Medicine: 59 (3)
Cleveland Clinic Journal of Medicine
Vol. 59, Issue 3
1 May 1992
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Pharmacotherapy of multiple sclerosis: current status
Richard A. Rudick, Donald E. Goodkin, Richard M. Ransohoff
Cleveland Clinic Journal of Medicine May 1992, 59 (3) 267-277;

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Pharmacotherapy of multiple sclerosis: current status
Richard A. Rudick, Donald E. Goodkin, Richard M. Ransohoff
Cleveland Clinic Journal of Medicine May 1992, 59 (3) 267-277;
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Keywords

  • Multiple Sclerosis
  • AZATHIOPRINE
  • Polymers
  • Cyclophosphamide
  • Cyclosporins
  • Interferons
  • Plasmapheresis
  • Lymphatic Irradiation

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