Table of Contents
Highlights from Medical Grand Rounds
- Contemporary Considerations in Exercise ECG Testing
Despite the promises of new technologies, ECG use is increasing and its clinical applications are diversifying.
- Trends in Noncardiac Chest Pain
The prognosis for patients with noncardiac chest pain is excellent, yet functional outcome is generally poor because many patients continue to believe their pain has a cardiac source.
CME Notebook
Current Drug Therapy
- Adrenergic agents: clinical trials and experiences
Different beta blockers have different effects on cardiac output and heart rate, and some may diminish detrimental arterial changes induced by hypertension. A long-term preventive effect against coronary artery disease remains to be demonstrated.
State of the art: Neurology
- A practical approach to coma diagnosis in the unresponsive patient
A chain of simple-to-make observations quickly determines the location of the lesion — the primary goal in early assessment.
Bench to Bedside
- Calcium-channel blocking agents as therapy for amphotericin B nephrotoxicity
Concomitant use of calcium-channel blockers may prevent nephrotoxicity and permit use of full therapeutic doses of amphotericin B in systemic fungal infection.
Review
- Pharmacotherapy of multiple sclerosis: current status
With careful drug selection and close monitoring, many symptoms associated with MS are effectively controlled.
- Doppler echocardiographic assessment of constrictive pericarditis, cardiac amyloidosis, and cardiac tamponade
Doppler echocardiography is emerging as an excellent noninvasive way to assess diastolic function, and its array of clinical applications is expanding.
- Primary angiitis of the central nervous system: diagnostic criteria and clinical approach
Clinical perceptions of PACNS have changed dramatically in the last 5 years, prompting a reappraisal of the 1987 diagnostic criteria and current approaches to treatment
- Lung and heart-lung transplantation: the state of the art
Lung and heart-lung transplantation is no longer experimental, but a reasonable option in many heart and lung disorders previously deemed fatal.
- Viral hepatitis in the 1990s, part I: current principles of management
An update of the clinical management of viral hepatitis, based on recent developments in screening and diagnosis.
Contributions
- Circadian rhythms and migraine
Migraine onset was found to parallel that of myocardial infarction and changes in platelet aggregability, plasma cortisol, and plasma catecholamines.
