The yin and yang of tumor necrosis factor inhibitors

  • Cleveland Clinic Journal of Medicine
  • March 2006,
  • 73
  • (3)
  • 251-256;

ABSTRACT

Tumor necrosis factor (TNF) inhibitors have proven highly effective against a number of autoimmune diseases but have been disappointing in treating others. An increase in the risk of Mycobacterium tuberculosis and other opportunistic infections has been noted in patients treated with these agents. If we use these drugs, we need to weigh their beneficial and adverse effects.

Footnotes

  • * The author has indicated that he has served as a consultant to the Abbott and Amgen corporations.

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