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Commentary

2017 ACC/AHA hypertension guidelines: Toward tighter control

Rebecca Blonsky, MD, Marc Pohl, MD, Joseph V. Nally, MD and George Thomas, MD
Cleveland Clinic Journal of Medicine October 2018, 85 (10) 771-778; DOI: https://doi.org/10.3949/ccjm.85a.18028
Rebecca Blonsky
Nephrologist, Marshfield Clinic, Marshfield, WI
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Marc Pohl
Consultant Staff, Department of Nephrology and Hypertension, Glickman Urological Institute, Cleveland Clinic
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Joseph V. Nally Jr
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George Thomas
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  • For correspondence: [email protected]
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    Figure 1

    With the 2017 guideline definition, the prevalence of hypertension is higher.

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    TABLE 1

    Classification of hypertension

    Systolic BP (mm Hg)Diastolic BP (mm Hg)JNC 7 (2003)ACC/AHA (2017)
    < 120and< 80NormalNormal
    120–129and< 80PrehypertensionElevated BP
    130–139or80–89PrehypertensionStage 1 hypertension
    140–159or90–99Stage 1 hypertensionStage 2 hypertension
    ≥ 160or≥ 100Stage 2 hypertensionStage 2 hypertension
    • ACC = American College of Cardiology; AHA = American Heart Association; BP = blood pressure; JNC = Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure

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    TABLE 2

    Blood pressure treatment guidelines compared

    GuidelineBlood pressure goals (mm Hg)Initial drug therapy
    JNC 7 (2003)3General population< 140/90Thiazide
    Chronic kidney disease< 130/80ACE inhibitor or ARB
    Diabetes mellitus< 130/80Thiazide, CCB, beta-blocker, ACE inhibitor, or ARB
    With proteinuria: ACE inhibitor or ARB
    NICE (2011)25General population< 140/90Black or age > 55: CCB, thiazide
    Nonblack or age ≤ 55: ACE inhibitor or ARB
    With proteinuria: ACE inhibitor or ARB
    Elderly (age ≥ 80)< 150/90
    Chronic kidney disease< 140/90
    Diabetes mellitus< 140/90aBlack: ACE inhibitor or ARB + CCB or thiazide
    Nonblack: ACE inhibitor or ARB
    With proteinuria: ACE inhibitor or ARB
    KDIGO (2012)29Chronic kidney disease with albuminuria
     < 30 mg/24 hoursb
    ≤ 140/90
     ≥ 30 mg/24 hoursb≤ 130/80ACE inhibitor or ARB
    ESH/ESC (2013)24General population< 140/90Thiazide, CCB, beta-blocker, ACE inhibitor or ARB
    Elderly (age ≥ 80)< 150/90
    Chronic kidney disease< 140/90Thiazide, CCB, beta-blocker, ACE inhibitor, or ARB
    With proteinuria: ACE inhibitor or ARB
    Diabetes mellitus< 140/85
    ASH/ISH (2014)28General population< 140/90Black: CCB or thiazide
    Nonblack, age < 60: ACE inhibitor or ARB
    Nonblack, age ≥ 60: CCB or thiazide
    Elderly (age ≥ 80)< 150/90
    Chronic kidney disease< 140/90ACE inhibitor or ARB
    Diabetes mellitus< 140/90ACE inhibitor or ARB
    Black: acceptable to start with CCB or thiazide
    JNC 8 (2014)5General population< 140/90Black, including those with diabetes: thiazide, CCB
    Nonblack, including those with diabetes: thiazide, CCB, ACE inhibitor, or ARB
    Older patients (age ≥ 60)< 150/90
    Diabetes mellitus< 140/90
    Chronic kidney disease< 140/90ACE inhibitor or ARB
    Hypertension Canada (2018)12General population< 140/90Thiazide, CCB, beta-blocker (in age < 60), ACE inhibitor (in nonblack), or ARB
    Chronic kidney disease< 140/90With proteinuria: ACE inhibitor or ARB
    Diabetes mellitus< 130/80Thiazide, CCB, ACE inhibitor, or ARB
    With proteinuria or renal disease: ACE inhibitor or ARB
    ACC/AHA (2017)1General population< 130/80Thiazide, CCB, ACE inhibitor, or
    ARB Black including diabetes, but no heart failure or chronic kidney disease: CCB, thiazide
    Older patients (age ≥ 65)< 130/80c
    Chronic kidney disease< 130/80Thiazide, CCB, ACE inhibitor, or ARB
    With proteinuria: ACE inhibitor or ARB
    Diabetes mellitus< 130/80
    ACP/AAFP (2017)27Older patients (age ≥ 60)< 150/90
    ADA (2017)30Diabetes mellitus< 140/90Thiazide, CCB, ACE inhibitor, or ARB
    With proteinuria: ACE inhibitor or ARB
    • ↵a < 130/80 if chronic kidney disease and diabetes mellitus;

    • ↵b Or equivalent;

    • ↵c Unless alternative goal determined by physician.

    • AAFP = American Academy of Family Physicians; ACC = American College of Cardiology; ACE = angiotensin-converting enzyme; ACP = American College of Physicians; ADA = American Diabetes Association; AHA = American Heart Association; ARB = angiotensin II receptor blocker; ASH = American Society of Hypertension; CCB = calcium channel blocker; ESC = European Society of Cardiology; ESH = European Society of Hypertension; ISH = International Society of Hypertension; JNC = Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure; KDIGO = Kidney Disease: Improving Global Outcomes; NICE = National Institute for Health and Care Excellence

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Cleveland Clinic Journal of Medicine: 85 (10)
Cleveland Clinic Journal of Medicine
Vol. 85, Issue 10
1 Oct 2018
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2017 ACC/AHA hypertension guidelines: Toward tighter control
Rebecca Blonsky, Marc Pohl, Joseph V. Nally, George Thomas
Cleveland Clinic Journal of Medicine Oct 2018, 85 (10) 771-778; DOI: 10.3949/ccjm.85a.18028

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2017 ACC/AHA hypertension guidelines: Toward tighter control
Rebecca Blonsky, Marc Pohl, Joseph V. Nally, George Thomas
Cleveland Clinic Journal of Medicine Oct 2018, 85 (10) 771-778; DOI: 10.3949/ccjm.85a.18028
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    • ACC AND AHA ARE NOW RESPONSIBLE FOR HYPERTENSION GUIDELINES
    • WHAT’S NEW IN THE 2017 GUIDELINES?
    • COMPARISONS WITH OTHER GUIDELINES
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