Current Drug Therapy

Hydroxychloroquine: An old drug with new relevance

Eugen Alexander Shippey, MD, Vanya D. Wagler, DO, FACP, FACR and Angelique N. Collamer, MD, FACP, FACR
Cleveland Clinic Journal of Medicine June 2018, 85 (6) 459-467; DOI: https://doi.org/10.3949/ccjm.85a.17034

ABSTRACT

Hydroxychloroquine is an immunomodulatory drug that has been used for 60 years to treat malaria and autoimmune diseases such as systemic lupus erythematosus and inflammatory arthritis, and potential new uses and benefits continue to emerge. Toxicity concerns have been addressed with updated prescribing recommendations.

Footnotes

  • The authors declare no commercial or financial conflicts of interest relative to this article. The views expressed in this article are those of the authors and do not necessarily reflect the official policy or position of the US Department of the Army, Department of the Air Force, the Uniformed Services University, the Department of Defense, or the US government.

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  1. Eugen Alexander Shippey III, MD⇑
  1. Resident, Department of Internal Medicine, William Beaumont Army Medical Center, El Paso, TX
  1. ADDRESS:
    Eugen Alexander Shippey III, MD, Department of Internal Medicine, William Beaumont Army Medical Center, 170 West Castellano Drive, Apt. 7120, El Paso, TX 79912; eugen.shippey{at}gmail.com
  1. Vanya D. Wagler, DO, FACP, FACR
  1. Department of Rheumatology, William Beaumont Army Medical Center, El Paso, TX
  1. Angelique N. Collamer, MD, FACP, FACR
  1. Chief, Department of Rheumatology, Walter Reed National Military Medical Center, Bethesda, MD

ABSTRACT

Hydroxychloroquine is an immunomodulatory drug that has been used for 60 years to treat malaria and autoimmune diseases such as systemic lupus erythematosus and inflammatory arthritis, and potential new uses and benefits continue to emerge. Toxicity concerns have been addressed with updated prescribing recommendations.

Footnotes

  • The authors declare no commercial or financial conflicts of interest relative to this article. The views expressed in this article are those of the authors and do not necessarily reflect the official policy or position of the US Department of the Army, Department of the Air Force, the Uniformed Services University, the Department of Defense, or the US government.

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