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Cleveland Clinic Journal of Medicine
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Cleveland Clinic Journal of Medicine

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Rheumatology

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    What diagnostic tests should be done after discovering clubbing in a patient without cardiopulmonary symptoms?
    Karthik Meiyappan Udayappan, MD and Christopher V. Anstine, MD
    Cleveland Clinic Journal of Medicine May 2025, 92 (5) 273-276; DOI: https://doi.org/10.3949/ccjm.92a.24052

    Computed tomography of the patient’s chest is indicated based on the robust association between clubbing and intrathoracic malignancy.

  • You have access
    All sulfa drugs are not created equal
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine March 2025, 92 (3) 136-137; DOI: https://doi.org/10.3949/ccjm.92b.03025

    Misinformation about “sulfa allergy” can result in unnecessary avoidance of useful medications and the prescription of less effective alternatives.

  • You have access
    Sarcoidosis with diffuse purplish erythematous plaques on the hands
    Akihiro Orita, MD and Mitsuhito Ota, MD, PhD
    Cleveland Clinic Journal of Medicine March 2025, 92 (3) 145-146; DOI: https://doi.org/10.3949/ccjm.92a.24022

    A 70-year-old woman presented in winter with a 1-month history of asymptomatic redness of the hands.

  • You have access
    Can my patient with a ‘sulfa allergy’ receive celecoxib or other nonantimicrobial sulfonamides?
    Nicholas B. Cline, MD, Amudha Pazhanisamy, DO and David M. Lang, MD
    Cleveland Clinic Journal of Medicine March 2025, 92 (3) 147-151; DOI: https://doi.org/10.3949/ccjm.92a.24054

    There is no cross-reactivity between antimicrobial and nonantimicrobial sulfonamides, and patients with a history of immunoglobulin E–mediated reaction to a sulfonamide antibiotic can receive nonantimicrobial sulfonamides.

  • You have access
    The causes of vascular insufficiency and Hickam vs Ockham
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine December 2024, 91 (12) 713-714; DOI: https://doi.org/10.3949/ccjm.91b.12024

    Is our reflexive search for a single explanatory diagnosis always reasonable and warranted—or is it truly “just” an academic intellectual exercise?

  • You have access
    A 74-year-old woman with purple toes
    Baila R. Elkin, MD and Megan McGervey, MD
    Cleveland Clinic Journal of Medicine December 2024, 91 (12) 735-741; DOI: https://doi.org/10.3949/ccjm.91a.24064

    While the patient was undergoing treatment for livedoid vasculopathy, her toes started to become purple and she experienced persistent “stinging” pain in her feet.

  • You have access
    Salt-and-pepper skin pigmentation
    Ramachandran Gnanasuriyan, MD, Savitha Murali, MD and Sheela Kuruvila, MD
    Cleveland Clinic Journal of Medicine October 2024, 91 (10) 593-594; DOI: https://doi.org/10.3949/ccjm.91a.24038

    Dermoscopy of the skin lesions revealed homogeneous depigmented areas with perifollicular pigmentation.

  • Incidentally detected noninfectious thoracic aortitis: A clinical approach
    You have access
    Incidentally detected noninfectious thoracic aortitis: A clinical approach
    CME article
    Alison H. Clifford, MD, MSc
    Cleveland Clinic Journal of Medicine October 2024, 91 (10) 621-633; DOI: https://doi.org/10.3949/ccjm.91a.24030

    The author reviews how aortitis is detected, its many possible causes, and the workup and treatment of patients who are found to have it.

  • You have access
    Sorting out aortic aneurysms: A team enterprise
    Gary S. Hoffman, MD, MS, MACR
    Cleveland Clinic Journal of Medicine October 2024, 91 (10) 635-637; DOI: https://doi.org/10.3949/ccjm.91a.24040

    Aortic aneurysms present considerable diagnostic and treatment challenges owing to their diverse causes, incomplete understanding of pathogenesis, and variations in presentation and disease course.

  • You have access
    Preventing herpes zoster in immunocompromised patients: Current concepts
    Cassandra Calabrese, DO, Elizabeth Kirchner, DNP, James Fernandez, MD, PhD and Leonard H. Calabrese, DO
    Cleveland Clinic Journal of Medicine July 2024, 91 (7) 437-445; DOI: https://doi.org/10.3949/ccjm.91a.24019

    The authors review clinical aspects of herpes zoster vaccination, including identifying at-risk patients, weighing the risks and benefits of the recombinant zoster vaccine, and using best practices for administering the vaccine.

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