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Cleveland Clinic Journal of Medicine
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Cleveland Clinic Journal of Medicine

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Rheumatology

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    The constellation of vitamin D, the acute-phase response, and inflammation
    Maria J. Antonelli, MD, Irving Kushner, MD and Murray Epstein, MD, FASN, FACP
    Cleveland Clinic Journal of Medicine February 2023, 90 (2) 85-89; DOI: https://doi.org/10.3949/ccjm.90a.22048

    An astronomic increase in vitamin D testing and supplementation is happening in the absence of an evidence-based rationale.

  • You have access
    Vitamin D: A metabolic bone disease perspective
    Bruce Long, MD, FACR, BS Pharm
    Cleveland Clinic Journal of Medicine February 2023, 90 (2) 91-92; DOI: https://doi.org/10.3949/ccjm.90a.22086

    When checking levels, clinicians should keep in mind that vitamin D levels fluctuate by season and time of day, and that different laboratories may use different assays that yield different results.

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    Bone turnover markers to monitor oral bisphosphonate therapy
    CME article
    Nikita Ashcherkin, MD, Archna A. Patel, MD, MPH, Alicia Algeciras-Schimnich, PhD and Krupa B. Doshi, MD, FACE
    Cleveland Clinic Journal of Medicine January 2023, 90 (1) 26-31; DOI: https://doi.org/10.3949/ccjm.90a.22002

    Rapid changes in levels of bone turnover markers can be useful in monitoring the effectiveness of therapy and improving adherence to therapy.

  • You have access
    Making best use of bone turnover markers to monitor oral bisphosphonate therapy
    Sarah Keller, MD
    Cleveland Clinic Journal of Medicine January 2023, 90 (1) 32-34; DOI: https://doi.org/10.3949/ccjm.90a.22092

    Clinical applications of bone turnover markers can include determining when to start or end a bisphosphonate “holiday” and measuring treatment response.

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    Nontuberculous mycobacterial musculoskeletal infections: Recognizable, when suspected
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine July 2022, 89 (7) 355-356; DOI: https://doi.org/10.3949/ccjm.89b.07022

    Two articles in this issue offer valuable insight into when to suspect these infections in patients who present with swollen, indurated, peripheral soft-tissue structures.

  • You have access
    Dactylitis from Mycobacterium intracellulare infection
    Hayato Shimizu, MD, Takumi Hashimura, MD and Hiroaki Nishioka, MD, PhD
    Cleveland Clinic Journal of Medicine July 2022, 89 (7) 360-362; DOI: https://doi.org/10.3949/ccjm.89a.21067

    A 69-year-old man presents with 6 months of progressive swelling of the right middle finger, with no systemic symptoms.

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    Unraveling a challenging diagnosis: Role of a TNF inhibitor
    Soumya Chatterjee, MD, MS, FRCP, FACP, FACR
    Cleveland Clinic Journal of Medicine July 2022, 89 (7) 368-370; DOI: https://doi.org/10.3949/ccjm.89a.21128

    Painful swelling of the dorsum of the right hand had been diagnosed as chronic cutaneous sarcoidosis with tenosynovitis, treated unsuccessfully with prednisone and methotrexate.

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    Treating anemia: It’s not just the EPO
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine April 2022, 89 (4) 174-175; DOI: https://doi.org/10.3949/ccjm.89b.04022

    Long-term effects of treatment with the new oral inhibitors of prolyl hydroxylase will need to be carefully monitored, as prolyl hydroxylase is a key structural component of diverse proteins.

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    Oral hyperpigmentation with weakness and salt-craving
    Joseph Zhou, MD and S. Sethu K. Reddy, MD, MBA, FRCPC, FACP, MACE
    Cleveland Clinic Journal of Medicine April 2022, 89 (4) 180-181; DOI: https://doi.org/10.3949/ccjm.89a.21036

    The patient’s primary care physician had attributed the hyperpigmentation on the lower lip and inner cheek to pen ink.

  • Anemia of chronic kidney disease: Will new agents deliver on their promise?
    You have access
    Anemia of chronic kidney disease: Will new agents deliver on their promise?
    Tarek Souaid, MD, Jonathan Taliercio, DO, James F. Simon, MD, MBA, Ali Mehdi, MD, MEd and Georges N. Nakhoul, MD, MEd
    Cleveland Clinic Journal of Medicine April 2022, 89 (4) 212-222; DOI: https://doi.org/10.3949/ccjm.89a.21100

    A review of the pathophysiology of anemia of chronic kidney disease, major clinical trials, and novel therapies.

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