Rheumatology
- Localized dead bone, a potential hint to an underlying condition
The discovery of osteonecrosis by imaging, whether the patient is symptomatic or not, warrants consideration for the presence of an underlying condition.
- Sclerotic lesions in the metadiaphysis regions of the knee
The patient presented with left knee pain located over her patella that had progressively worsened over 4 months.
- Complement inhibition: A whole new world
As these medications enter the mainstream, understanding the complement system and the benefits and risks of therapeutic blockade has become crucial for optimal patient care.
- Clinical application of the complement system: A historical perspective
Now that our understanding of complement has evolved to therapeutic targeting of components of the cascade in a wide range of diseases, it is time to give the complement system another look.
- ‘Boxing glove’ hands in a patient initially diagnosed with RS3PE syndrome
The patient had edema that limited finger flexion, impairing daily tasks such as putting on socks.
- Multicentric reticulohistiocytosis
A 58-year-old man presented with a 2-month history of joint pain and swelling and a rash.
- What is the optimal time for bone density screening in patients with premature ovarian insufficiency?
Dual-energy x-ray absorptiometry should be performed at diagnosis, with the timing of repeat scans predicated on the patient’s clinical risk factors for fracture.
- MDA5 dermatomyositis: Unveiling a potentially life-threatening disease
Timely diagnosis and initiation of aggressive immunosuppressive therapy are key to improving the 40% overall mortality rate in patients with MDA5 dermatomyositis.
- Collaborative musculoskeletal care: The role for chiropractors
Integrating chiropractors into multidisciplinary care settings can help support guideline-concordant care and may free up internists to see more patients with other problems.