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Symptoms to Diagnosis

A young man with acute chest pain

Amir Farid, MD, Neil Beri, MD, David Torres-Barba, MD, PhD and Charles Whitcomb, MD
Cleveland Clinic Journal of Medicine September 2019, 86 (9) 586-594; DOI: https://doi.org/10.3949/ccjm.86a.19025
Gregory W. Rutecki
Department of Cardiology, University of California Davis Medical Center, Sacramento
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Amir Farid
Department of Cardiology, University of California Davis Medical Center, Sacramento
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Neil Beri
Department of Cardiology, University of California Davis Medical Center, Sacramento
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David Torres-Barba
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  • For correspondence: [email protected]
Charles Whitcomb
Department of Cardiology, University of California Davis Medical Center, Sacramento
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    Figure 1

    The patient’s electrocardiogram on presentation shows ST-segment elevation (arrows) over the lateral and inferior distribution (V4–V6, II, III, and aVF).

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    Figure 2

    Cardiac magnetic resonance imaging shows areas of patchy subepicardial late gadolinium enhancement (arrows).

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    Figure 3

    Our suggested approach to suspected acute myocarditis.

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    TABLE 1

    Selected causes of myocarditis

    INFECTIOUS
    Viral
    Parvovirus B19
    Coxsackie B (enterovirus)
    Adenovirus
    Human herpesviruses
     Cytomegalovirus
     Epstein-Barr virus,
     Human herpes virus 6
    Human immunodeficiency virus
    Influenza A/B
    Poliovirus
    Hepatitis C
    Bacterial
    Borrelia
    Rickettsia
    Coxiella
    Staphylococcus
    Streptococcus
    Corynebacterium diphtheria
    Mycobacterium
    Protozoal
    Trypanosoma cruzi
    Toxoplasma
    Babesia
    Parasitic
    Trichinella spiralis
    Taenia solium
    Fungal
    Aspergillus
    Candida
    Histoplasma
    Mucormycosis
    Sporothirix
    IMMUNE-MEDIATED
    Allergens
    Tetanus toxoid
    Vaccines (especially smallpox)
    Serum sickness
    Autoantigens
    Infection-negative giant cell
    Systemic lupus erythematosus
    Rheumatoid arthritis
    Sarcoidosis
    Alloantigens
    Heart transplant rejection
    TOXIC
    Drugs
    Amphetamines
    Cocaine
    Lithium
    Clozapine
    Anthracyclines (doxorubicin)
    Mesalamine
    Sulfonamides (hypersensitivity)
    Penicillins (hypersensitivity)
    Immune checkpoint inhibitors (ipilimumab, pembrolizumab, nivolumab)
    Heavy metals
    Iron
    Copper
    Lead (rare)
    Physical agents
    Radiation
    Hormones
    Pheochromocytoma (epinephrine, norepinephrine)
    Miscellaneous
    Insect bites
    Scorpion sting
    Inhalants
    Arsenic
    • Based on information in references 3, 21, and 22.

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Cleveland Clinic Journal of Medicine: 86 (9)
Cleveland Clinic Journal of Medicine
Vol. 86, Issue 9
1 Sep 2019
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A young man with acute chest pain
Amir Farid, Neil Beri, David Torres-Barba, Charles Whitcomb
Cleveland Clinic Journal of Medicine Sep 2019, 86 (9) 586-594; DOI: 10.3949/ccjm.86a.19025

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A young man with acute chest pain
Amir Farid, Neil Beri, David Torres-Barba, Charles Whitcomb
Cleveland Clinic Journal of Medicine Sep 2019, 86 (9) 586-594; DOI: 10.3949/ccjm.86a.19025
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  • Article
    • FURTHER TESTING
    • CASE CONTINUED
    • INFECTIOUS CAUSES OF MYOCARDITIS
    • TREATMENT FOR MYOCARDITIS
    • CASE CONTINUED
    • DISCHARGE INSTRUCTIONS
    • CASE CONCLUDED
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