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Review

Soft tissue sarcoma: Recognizing a rare disease

Amir Hossain Gahanbani Ardakani, BSc, MBBS, Alex Woollard, BM, BSc, PhD, FRCS (Plast), Howard Ware, MBBS, FRCS (Tr&Orth) and Panagiotis Gikas, MBBS Hons, MD (Res), PhD, FRCS (Tr&Orth)
Cleveland Clinic Journal of Medicine February 2022, 89 (2) 73-80; DOI: https://doi.org/10.3949/ccjm.89a.21078
Amir Hossain Gahanbani Ardakani
Department of Orthopaedic Oncology, Royal National Orthopaedic Hospital, Stanmore, UK
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  • For correspondence: [email protected]
Alex Woollard
Department of Plastic Surgery, Royal National Orthopaedic Hospital, Stanmore, UK; Royal Free Hospital, London, UK
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Howard Ware
Department of Orthopaedic Surgery, Cleveland Clinic, London, UK
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Panagiotis Gikas
Department of Orthopaedic Oncology, Royal National Orthopaedic Hospital, Stanmore, UK
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    TABLE 1

    Clinical features of soft tissue masses that require urgent investigation

    Increasing size
    Size greater than 5 cm (ie, golf-ball size)
    Deeper-lying mass (deep to fascia)
    Firmer than surrounding tissue
    Patient has potential risk factors (previous radiotherapy, chronic lymphedema, inherited syndrome such as Gardner syndrome, Li-Fraumeni syndrome, and von Recklinghausen disease)
    Local symptoms and signs of infiltration
    With or without pain (large painless lumps should raise concern)
    The greater the number of clinical features, the greater the risk of malignancy.
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Cleveland Clinic Journal of Medicine: 89 (2)
Cleveland Clinic Journal of Medicine
Vol. 89, Issue 2
1 Feb 2022
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Soft tissue sarcoma: Recognizing a rare disease
Amir Hossain Gahanbani Ardakani, Alex Woollard, Howard Ware, Panagiotis Gikas
Cleveland Clinic Journal of Medicine Feb 2022, 89 (2) 73-80; DOI: 10.3949/ccjm.89a.21078

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Soft tissue sarcoma: Recognizing a rare disease
Amir Hossain Gahanbani Ardakani, Alex Woollard, Howard Ware, Panagiotis Gikas
Cleveland Clinic Journal of Medicine Feb 2022, 89 (2) 73-80; DOI: 10.3949/ccjm.89a.21078
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  • Article
    • ABSTRACT
    • THE EPIDEMIOLOGY OF SOFT TISSUE SARCOMA
    • CHALLENGES TO CLINICAL RECOGNITION OF SOFT TISSUE SARCOMA
    • FEATURES THAT GUIDE THE DIFFERENTIAL DIAGNOSIS
    • WHICH DIAGNOSTIC TESTS ARE PREFERABLE?
    • AVOIDING A ‘WHOOPS PROCEDURE’
    • LITIGATION AND COST
    • TAKE-HOME MESSAGE
    • DISCLOSURES
    • REFERENCES
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