Dermatology
- Allopurinol hypersensitivity is rare, bad, and partially avoidable, but allopurinol can still be used effectively
The shadow of the 1984 Hande et al guidelines still hangs over clinical decision-making when managing allopurinol dosing in patients with gout and chronic kidney disease.
- Severe cutaneous reaction induced by allopurinol
Three weeks after starting allopurinol for gout, an 86-year-old woman presented with a maculopapular rash and painful blistering and erosions of the oral mucosa.
- Amoxicillin rash in infectious mononucleosis
A 23-year-old woman developed a rash on the day she completed a 10-day course of amoxicillin for group A streptococcal infection.
- Sarcoidosis with diffuse purplish erythematous plaques on the hands
A 70-year-old woman presented in winter with a 1-month history of asymptomatic redness of the hands.
- Vesicular pityriasis rosea
A 37-year-old man presented with a 9-day history of disseminated pruritic rash on his trunk and extremities.
- The causes of vascular insufficiency and Hickam vs Ockham
Is our reflexive search for a single explanatory diagnosis always reasonable and warranted—or is it truly “just” an academic intellectual exercise?
- Oral condylomata lata
The patient had a 3-month history of painless oral lumps and intermittent sore throat.
- A 74-year-old woman with purple toes
While the patient was undergoing treatment for livedoid vasculopathy, her toes started to become purple and she experienced persistent “stinging” pain in her feet.
- Salt-and-pepper skin pigmentation
Dermoscopy of the skin lesions revealed homogeneous depigmented areas with perifollicular pigmentation.