Oncology

  • Mucinous ascites: Pseudomyxoma peritonei
    Sansrita Nepal, MD, Adam Schwertner, MD and John M. Cunningham, MD
    Cleveland Clinic Journal of Medicine September 2022, 89 (9) 491-493; DOI: https://doi.org/10.3949/ccjm.89a.21086

    A 59-year-old man presented with progressive abdominal distention that limited daily activities and oral intake. The ascitic fluid was markedly viscous and jelly-like.

  • What are the considerations in patient selection and timing of risk-reducing mastectomy?
    Holly J. Pederson, MD, Allison W. Kurian, MD, MSc and Zahraa Al Hilli, MD
    Cleveland Clinic Journal of Medicine August 2022, 89 (8) 442-444; DOI: https://doi.org/10.3949/ccjm.89a.21114

    The option of risk-reducing mastectomy is for those at highest risk, and multidisciplinary conversations setting patient expectations are critical for optimal patient outcomes.

  • Metastatic bone disease: Early referral for multidisciplinary care
    Amir Hossain Gahanbani Ardakani, BSc, MBBS, Martina Faimali, MBBS, FRCS (Tr&Orth), Lukas Nystrom, MD, Nathan Mesko, MD, Muntzer Mughal, MBChB, ChM, FRCS, Howard Ware, MBBS, FRCS (Tr&Orth) and Panagiotis Gikas, BSc, MBBS Hons, MD (Res), PhD, FRCS (Tr&Orth)
    Cleveland Clinic Journal of Medicine July 2022, 89 (7) 393-399; DOI: https://doi.org/10.3949/ccjm.89a.21062

    A lack of awareness and recognition of symptoms continues to delay referral to specialist teams. The authors provide guidance for early diagnosis and referral.

  • Pigmented lesion on nail bed: Pseudo-Hutchinson sign
    Yahya Daneshbod, MD, Majid Akrami, MD, Sara Fanaee, MD, Komeil Mirzaei Baboli, MD and Hadi Mirfazaelian, MD
    Cleveland Clinic Journal of Medicine June 2022, 89 (6) 303-304; DOI: https://doi.org/10.3949/ccjm.89a.21070

    The discoloration had been present since the patient was 14, and it had not changed in appearance.

  • Lacrimal gland involvement in a patient with sarcoidosis
    Tanmayi Pai, MD, Mohamed S. Muneer, MD, Kafayat Oyemade, Diva R. Salomao, MD, Vivek Gupta, MD and Dana Harris, MD
    Cleveland Clinic Journal of Medicine May 2022, 89 (5) 239-240; DOI: https://doi.org/10.3949/ccjm.89a.21037

    The differential diagnosis included infection, malignancy, and inflammatory disorders such as immunoglobulin G4-related disease and sarcoidosis.

  • A brownish erythematous patch in the nipple-areola complex
    Irene López Riquelme, MD, Elisabeth Gómez Moyano, MD, PhD, María Ayala Blanca, PhD and Leandro Martínez Pilar, MD, PhD
    Cleveland Clinic Journal of Medicine May 2022, 89 (5) 241-242; DOI: https://doi.org/10.3949/ccjm.89a.21059

    Biopsy revealed neoplastic cells throughout the epidermis and granular layer, with abundant pale cytoplasm, intraglandular extension, and chronic inflammation in the papillary dermis.

  • Palliative care: An update for internists
    Rachel D. Havyer, MD, FAAHPM, Nauzley Abedini, MD, MSc, Robert L. Jayes, MD, Brenda Matti-Orozco, MD, Daniel H. Pomerantz, MD, MPH and Aziz A. Ansari, DO, SFHM, FAAHPM, FACP
    Cleveland Clinic Journal of Medicine May 2022, 89 (5) 262-268; DOI: https://doi.org/10.3949/ccjm.89a.21075

    A review of recent research to guide symptom management, advance-care planning, and communication training to maximize compassionate care.

  • Esophageal adenocarcinoma: A dire need for early detection and treatment
    Esophageal adenocarcinoma: A dire need for early detection and treatment
    CME article
    Abel Joseph, MD, Siva Raja, MD, PhD, Suneel Kamath, MD, Sunguk Jang, MD, Daniela Allende, MD, Mike McNamara, MD, Gregory Videtic, MD, Sudish Murthy, MD and Amit Bhatt, MD
    Cleveland Clinic Journal of Medicine May 2022, 89 (5) 269-279; DOI: https://doi.org/10.3949/ccjm.89a.21053

    A clinical overview focused on screening, multidisciplinary evaluation, and treatment of early esophageal adenocarcinoma.

  • Treating anemia: It’s not just the EPO
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine April 2022, 89 (4) 174-175; DOI: https://doi.org/10.3949/ccjm.89b.04022

    Long-term effects of treatment with the new oral inhibitors of prolyl hydroxylase will need to be carefully monitored, as prolyl hydroxylase is a key structural component of diverse proteins.

  • Capsule endoscopy in gastrointestinal disease: Evaluation, diagnosis, and treatment
    Basil Akpunonu, MD, Jeannine Hummell, CNP, Joseph D. Akpunonu and Shahab Ud Din, MD
    Cleveland Clinic Journal of Medicine April 2022, 89 (4) 200-211; DOI: https://doi.org/10.3949/ccjm.89a.20061

    The procedure is mainly used to evaluate obscure bleeding in the small bowel, but it is also used in the evaluation and diagnosis of a wide range of gastrointestinal conditions.

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