Oncology
- Immunotherapy meets William Shakespeare
Immune checkpoint inhibitors are potentially life-saving therapies that can trigger a wide range of autoimmune pathology.
- How should I manage my patient with cancer who is experiencing diarrhea while on immunotherapy?
Diarrhea and colitis, which can result from infection or be complications of immune checkpoint inhibitors, require prompt evaluation so that appropriate treatment can be started.
- Breast cancer risk and screening for transgender and gender-diverse individuals
Evidence on breast cancer risk in transgender and gender-diverse individuals is limited, and recent guidelines are primarily based on expert consensus, retrospective cohort studies, and extrapolation from cisgender populations.
- Cervical cancer screening in high-risk patients: Clinical challenges in primary care
The authors provide up-to-date guidance on cervical cancer screening, surveillance, and management for high-risk patients.
- Hematologic complications after kidney and pancreas transplant in a patient with chronic myeloid leukemia
This case highlights the complex interplay linking autoimmunity, solid-organ transplant, myeloid neoplasm, and Evans syndrome.
- Management of venous thromboembolism in patients with active cancer
The authors review the presentation and diagnosis of venous thromboembolism in patients with cancer and present an approach to treatment that aims to balance the bleeding risk from anticoagulation with the risk of recurrent thrombosis.
- Gastric intestinal metaplasia and gastric cancer prevention: Watchful waiting
Malignancy develops in only a small minority of patients with gastric intestinal metaplasia. Recognition of clinical, endoscopic, and histologic features linked with cancer development is critical to identifying patients who require endoscopic surveillance.
- Cutaneous metastasis from gastric carcinoma
The patient presented with asymptomatic nodules and alopecia of the scalp 3 years after treatment for gastric adenocarcinoma.
- Unilateral green pleural effusion in a 22-year-old woman
Chills, night sweats, palpitations, and a 5-lb weight loss, preceded by 6 months of progressive dyspnea, fatigue, and reduced exercise tolerance. What is the diagnosis?